Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2273802 | 0.85 | HTR2A (0.53) | DRD2HTR7HTR2ACHRM3ATM | |
| SCHEMBL2279423 | 0.74 | HTR2A (0.52) | HTR7HTR2ACCNT1CDK9 | |
| SCHEMBL8304330 | 0.72 | DRD2 (0.78) | DRD2HTR7MEN1KMT2ADRD4 | |
| SCHEMBL10276962 | 0.72 | HTR2C (0.47) | DRD2KMT2ADRD4 | |
| SCHEMBL12125022 | 0.71 | DRD2 (0.59) | DRD2MEN1KMT2ADRD4HTR2A | |
| SCHEMBL2271779 | 0.71 | HTR1A (0.63) | DRD2HTR7MEN1KMT2ADRD4 | |
| SCHEMBL17840333 | 0.67 | CHRM3 (0.40) | CHRM3 | |
| SCHEMBL17840227 | 0.67 | CHRM3 (0.40) | CHRM3 | |
| SCHEMBL3958057 | 0.67 | ACHE (0.52) | HTR7 | |
| SCHEMBL30878617 | 0.67 | DRD3 (0.65) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059390-A1 | MODULATORS OF SEROTONIN RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | claimed |