Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840495 | 0.90 | GRM5 (0.43) | GRM5RAB9AFAAHEPHX1NPC1 | |
| SCHEMBL3373020 | 0.86 | GRM5 (0.46) | GRM5RAB9ANPC1 | |
| SCHEMBL3374792 | 0.86 | GRM5 (0.46) | GRM5RAB9ANPC1 | |
| SCHEMBL990812 | 0.85 | RAB9A (0.55) | GRM5RAB9ANPC1MAOB | |
| SCHEMBL3374718 | 0.84 | GRM5 (0.46) | GRM5RAB9ANPC1 | |
| SCHEMBL3374694 | 0.84 | GRM5 (0.46) | GRM5RAB9ANPC1 | |
| SCHEMBL3376064 | 0.83 | GRM5 (0.44) | GRM5RAB9ANPC1 | |
| SCHEMBL3374797 | 0.83 | GRM5 (0.44) | GRM5RAB9ANPC1 | |
| SCHEMBL3378272 | 0.82 | GRM5 (0.42) | GRM5RAB9AEPHX1NPC1MAOB | |
| SCHEMBL3379028 | 0.81 | GRM5 (0.46) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877365-B1 | ACETYLENE DERIVATIVES | NOVARTIS AG (CH) | 2010-11-10 | — | — | EP | claimed |