Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.75 |
| ▸ | DRD1 | P21728 | 3/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.75 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.75 |
| ▸ | HTR1A | P08908 | 2/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.75 |
| ▸ | DRD3 | P35462 | 2/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.75 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.75 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680918 | 0.93 | CYP3A4 (0.66) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| SCHEMBL2846050 | 0.93 | CYP3A4 (0.66) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| SCHEMBL30958564 | 0.91 | ABCB11 (0.90) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| SCHEMBL5477290 | 0.91 | ABCB11 (0.90) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| SCHEMBL30471867 | 0.88 | ABCB11 (0.82) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| SCHEMBL5477299 | 0.88 | ABCB11 (0.82) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| Benzene SCHEMBL3268864 | 0.88 | ABCB11 (0.82) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| SCHEMBL3183503 | 0.88 | ABCB11 (0.82) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| SCHEMBL3181827 | 0.88 | CYP3A4 (0.85) | CYP3A4NR1I2ABCB11TBXA2RADRA1A | |
| Amlodipine SCHEMBL6650712 | 0.87 | TBXA2R (0.98) | CYP3A4NR1I2ABCB11TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9314454-B2 | Oral cavity disintegrating tablet and method of producing the same | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 2016-04-19 | — | — | US | disclosed |
| EP-2233129-B1 | ORAL CAVITY DISINTEGRATING TABLET AND METHOD OF PRODUCING THE SAME | SAWAI SEIYAKU KK (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-20100278930-A1 | ORAL CAVITY DISINTEGRATING TABLET AND METHOD OF PRODUCING THE SAME | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| EP-2233129-A1 | ORAL CAVITY DISINTEGRATING TABLET AND METHOD OF PRODUCING THE SAME | Sawai Pharmaceutical Co., Ltd. (JP) | 2010-09-29 | — | — | EP | disclosed |