Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL6453701 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL17835406 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL6231749 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20240890 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL7046508 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28803923 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20240893 | 0.97 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL2969867 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2ALDH1A1ALOX15 | |
| Benzoic Acid SCHEMBL164261 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2ALDH1A1ALOX15 | |
| Terephthalic Acid SCHEMBL23270885 | 0.89 | TP53 (0.61) | TSHRTP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3585822-B1 | PROCESSES FOR MAKING POLYISOBUTYLENE COMPOSITIONS | NTP TEC LLC (US) | 2025-05-07 | — | — | EP | claimed |
| CN-113956471-B | Method for synthesizing high-temperature nylon under low pressure | 深圳市源之诚塑胶有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-114957973-B | Automobile water chamber material and preparation method thereof | 江门市德众泰尼龙有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-115506047-B | High-strength wig and preparation method thereof | 邵阳深镁科技时尚有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-111748092-B | Polyester amide, preparation method thereof and product fiber thereof | 上海凯赛生物技术股份有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-115506047-A | High-strength wig and preparation method thereof | 邵阳深镁科技时尚有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114957973-A | Automobile water chamber material and preparation method thereof | 江门市德众泰尼龙有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-110423344-B | Preparation method of low-volatile high-fluidity high-temperature nylon | 四川斯派恩新材料有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-112029277-B | Low-mold-fouling halogen-free flame-retardant reinforced high-temperature nylon material and preparation method thereof | 金旸（厦门）新材料科技有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-113956471-A | Method for synthesizing high-temperature nylon under low pressure | 深圳市源之诚塑胶有限公司 | 2022-01-21 | — | — | CN | claimed |
| EP-0583782-A1 | Connector | YAZAKI CORPORATION (JP) | 1994-02-23 | — | — | EP | claimed |
| EP-0109145-B1 | COMPATIBLE POLYMER BLENDS OF IMIDIZED ACRYLIC POLYMER AND POLYAMIDE AND THEIR USE IN THE PRODUCTION OF PLASTIC ARTICLES | ROHM AND HAAS COMPANY (US) | 1989-09-20 | — | — | EP | claimed |
| US-4619803-A | Self-texturing nylon yarn spinning process | MONSANTO COMPANY (US) | 1986-10-28 | — | — | US | claimed |
| EP-0170645-A2 | Self-texturing nylon yarn | Monsanto Company (US) | 1986-02-05 | — | — | EP | claimed |
| EP-0034757-B1 | PROCESS FOR MANUFACTURING POLYAMIDE FILMS | BASF Aktiengesellschaft (DE) | 1985-05-02 | — | — | EP | claimed |
| US-4501882-A | ADDING BASE TO POLYMERIZATION VESSEL BETWEEN BATCHES | MONSANTO COMPANY (US) | 1985-02-26 | — | — | US | claimed |
| EP-0109145-A2 | Compatible polymer blends of imidized acrylic polymer and polyamide and their use in the production of plastic articles | ROHM AND HAAS COMPANY (US) | 1984-05-23 | — | — | EP | claimed |
| US-4415706-A | N-HETEROCYCLIC POLYMERS FROM AMMONIA-OR PRIMARY AMINE-MODIFIED ACRYLIC ESTER POLYMERS; NYLON; MOLDING MATERIALS | ROHM AND HAAS COMPANY (US) | 1983-11-15 | — | — | US | claimed |
| EP-0034757-A2 | Process for manufacturing polyamide films | BASF Aktiengesellschaft (DE) | 1981-09-02 | — | — | EP | claimed |
| US-4113708-A | Melt preparation of 6TA/6IA polymers with phosphorus compound to reduce ammonia formation | MONSANTO COMPANY (US) | 1978-09-12 | — | — | US | claimed |