Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL2969867 | 1.00 | TSHR (0.64) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL9736567 | 0.92 | TSHR (0.54) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL7046508 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL20240890 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL6231749 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL28803923 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL337710 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL6453701 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL17835406 | 0.91 | TSHR (0.60) | TSHRDAONAPRTCES1CES2 | |
| Tetradecylamine SCHEMBL235412 | 0.90 | CES2 (0.54) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145921-B1 | Vulcanizable polymer compositions | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-01-25 | — | — | EP | claimed |
| EP-2199326-B1 | Vulcanizable polymer compositions | LANXESS DEUTSCHLAND GMBH (DE) | 2014-10-29 | — | — | EP | claimed |
| CN-101845157-B | Vulcanizable polymer compositions | LANXESS DEUTSCHLAND GMBH | 2014-07-09 | — | — | CN | claimed |
| CN-101845157-A | Vulcanizable polymer compositions | LANXESS DEUTSCHLAND GMBH | 2010-09-29 | — | — | CN | claimed |
| CN-101629005-A | Vulcanizable polymer composition | LANXESS DEUTSCHLAND GMBH | 2010-01-20 | — | — | CN | claimed |
| US-12630750-B2 | Adhesive compositions | ExxonMobil Technology and Engineering Company (US) | 2026-05-19 | — | — | US | disclosed |
| EP-3101065-B1 | CROSS-LINKABLE NITRILE RUBBER COMPOSITION AND CROSS-LINKED RUBBER | ZEON CORP (JP) | 2025-05-28 | — | — | EP | disclosed |
| EP-3124511-B1 | NITRILE GROUP-CONTAINING COPOLYMER RUBBER, CROSSLINKABLE RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT | ZEON CORP (JP) | 2025-04-02 | — | — | EP | disclosed |
| CN-119403872-A | Rubber composition, and rubber product and hose using the same | 住友理工株式会社 | 2025-02-07 | — | — | CN | disclosed |
| US-20240317966-A1 | RUBBER COMPOSITION, AND RUBBER PRODUCT AND HOSE EACH OBTAINED USING SAID RUBBER COMPOSITION | SUMITOMO RIKO COMPANY LIMITED (JP) | 2024-09-26 | — | — | US | disclosed |
| CN-118369376-A | Rubber composition, and rubber product and hose obtained using same | 住友理工株式会社 | 2024-07-19 | — | — | CN | disclosed |
| WO-2024070622-A1 | CARBOXYL GROUP-CONTAINING ACRYLIC RUBBER COMPOSITION AND CROSSLINKED PRODUCT THEREOF | 株式会社大阪ソーダ | 2024-04-04 | — | — | WO | disclosed |
| US-5412034-A | Curable elastomeric blends | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| US-4520169-A | IMPROVED PROCESSABILITY BY BLENDING SOFT ELASTOMER WITH TERPOLYMER OF ETHYLENE, CARBON MONOXIDE, AND UNSATURATED MONOMER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| US-4520183-A | Process for making random ethylene/alkyl acrylate copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0113904-A2 | Improved process for making random ethylene alkyl acrylate copolymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-07-25 | — | — | EP | disclosed |
| EP-0106982-A2 | Elastomeric sol/gel blends | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-02 | — | — | EP | disclosed |
| EP-0004442-B1 | IMPROVED ELASTOMERIC ETHYLENE/CARBOXYLIC ACID COPOLYMER, A PROCESS FOR ITS PREPARATION; VULCANIZABLE COMPOSITIONS CONTAINING THE COPOLYMER AND VULCANIZED ARTICLES PREPARED THEREFROM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-10-20 | — | — | EP | disclosed |
| US-4304887-A | CHROMIUM/III/ CARBOXYLATE OR TRIS/2*-HYDROXYACETOPHENONO/CHROMIUM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| EP-0004442-A1 | Improved elastomeric ethylene/carboxylic acid copolymer, a process for its preparation; vulcanizable compositions containing the copolymer and vulcanized articles prepared therefrom | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630750-B2 | Adhesive compositions | L1CAM, ITGAM, ICAM1 | TSHR 4426/4885DAO 4764/4885NAPRT 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.