Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL6453701 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL17835406 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL6231749 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20240890 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL337710 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28803923 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20240893 | 0.97 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL2969867 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2ALDH1A1ALOX15 | |
| Benzoic Acid SCHEMBL164261 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2ALDH1A1ALOX15 | |
| Terephthalic Acid SCHEMBL23270885 | 0.89 | TP53 (0.61) | TSHRTP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030145929-A1 | Pneumatic radial tire | KANENARI DAISUKE (JP) | 2003-08-07 | — | — | US | disclosed |
| US-20010010245-A1 | Pneumatic radial tire | THE YOKOHAMA RUBBER CO., LTD. | 2001-08-02 | — | — | US | disclosed |
| EP-0095893-B2 | Polyamide elastomer | TORAY INDUSTRIES (JP) | 1994-04-20 | — | — | EP | disclosed |
| EP-0095893-B1 | POLYAMIDE ELASTOMER | TORAY INDUSTRIES, INC. (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0073557-B1 | COPOLYAMIDE, PROCESS FOR PRODUCING THEREOF AND COPOLYAMIDE MOLDING COMPOSITION COMPRISING THEREOF | TORAY INDUSTRIES, INC. (JP) | 1985-09-25 | — | — | EP | disclosed |
| US-4471088-A | MOLDING MATERIALS, HEXAMETHYLENEDIAMINE, UNDECAMETHYLENEDIAMINE | TORAY INDUSTRIES, INC. (JP) | 1984-09-11 | — | — | US | disclosed |
| US-4438240-A | THERMOPLASTIC POLYETHER-ESTER-AMIDE | TORAY INDUSTRIES, INCORPORATED (JP) | 1984-03-20 | — | — | US | disclosed |
| EP-0095893-A2 | Polyamide elastomer | TORAY INDUSTRIES, INC. (JP) | 1983-12-07 | — | — | EP | disclosed |
| EP-0073557-A1 | Copolyamide, process for producing thereof and copolyamide molding composition comprising thereof | TORAY INDUSTRIES, INC. (JP) | 1983-03-09 | — | — | EP | disclosed |