Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990118 | 0.86 | GRM5 (0.45) | GRM5RAB9ANPC1 | |
| SCHEMBL3374841 | 0.82 | GRM5 (0.44) | ALDH1A1GRM5FAAHRAB9A | |
| SCHEMBL3373542 | 0.81 | GRM5 (0.42) | GRM5FAAHEPHX1 | |
| SCHEMBL3377997 | 0.80 | GRM5 (0.42) | ALDH1A1GRM5FAAHRAB9ANPC1 | |
| SCHEMBL3374407 | 0.80 | GRM5 (0.45) | ALDH1A1GRM5FAAHEPHX1RAB9A | |
| SCHEMBL3374691 | 0.80 | GRM5 (0.45) | ALDH1A1GRM5FAAHEPHX1RAB9A | |
| SCHEMBL3378009 | 0.80 | GRM5 (0.45) | ALDH1A1GRM5FAAHEPHX1RAB9A | |
| SCHEMBL3374797 | 0.79 | GRM5 (0.44) | GRM5RAB9ANPC1 | |
| SCHEMBL3376064 | 0.79 | GRM5 (0.44) | GRM5RAB9ANPC1 | |
| SCHEMBL3412769 | 0.78 | GRM5 (0.46) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877365-B1 | ACETYLENE DERIVATIVES | NOVARTIS AG (CH) | 2010-11-10 | — | — | EP | claimed |