Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377248 | 0.86 | GRM5 (0.46) | GRM5 | |
| SCHEMBL3412769 | 0.86 | GRM5 (0.46) | GRM5 | |
| SCHEMBL990236 | 0.85 | GRM5 (0.43) | GRM5 | |
| SCHEMBL992116 | 0.85 | GRM5 (0.43) | GRM5 | |
| SCHEMBL3373542 | 0.81 | GRM5 (0.42) | GRM5FAAH | |
| SCHEMBL3374841 | 0.80 | GRM5 (0.44) | GRM5ALDH1A1RAB9AFAAH | |
| SCHEMBL3377251 | 0.80 | ALDH1A1 (0.43) | GRM5KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL3378683 | 0.80 | GRM5 (0.44) | GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3376528 | 0.80 | GRM5 (0.44) | GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3376495 | 0.79 | GRM5 (0.43) | GRM5NPC1RAB9AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877365-B1 | ACETYLENE DERIVATIVES | NOVARTIS AG (CH) | 2010-11-10 | — | — | EP | claimed |