Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377159 | 0.90 | HRH3 (0.41) | KMT2AMEN1BCHEHRH3POLB | |
| Hydrochloric Acid SCHEMBL3380052 | 0.89 | HRH3 (0.39) | KMT2AMEN1HRH3POLBKDM4E | |
| Hydrochloric Acid SCHEMBL3380054 | 0.89 | HRH3 (0.39) | KMT2AMEN1HRH3POLBKDM4E | |
| SCHEMBL3378145 | 0.89 | KDM4E (0.45) | KMT2AMEN1BCHEKDM4EALDH1A1 | |
| SCHEMBL3377784 | 0.87 | MEN1 (0.46) | KMT2AMEN1BCHEHRH3POLB | |
| SCHEMBL3377782 | 0.87 | MEN1 (0.46) | KMT2AMEN1BCHEHRH3POLB | |
| SCHEMBL3381553 | 0.85 | MEN1 (0.43) | KMT2AMEN1BCHEHRH3KDM4E | |
| SCHEMBL3380259 | 0.82 | HRH3 (0.45) | KMT2AMEN1BCHEHRH3KDM4E | |
| SCHEMBL3380460 | 0.81 | KCNH2 (0.45) | KMT2AMEN1BCHEHRH3KDM4E | |
| SCHEMBL3380792 | 0.81 | HRH3 (0.39) | BCHEHRH3KDM4EALDH1A1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |