Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377159 | 0.89 | HRH3 (0.41) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3377536 | 0.89 | KMT2A (0.38) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3377861 | 0.86 | KDM4E (0.43) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3380259 | 0.82 | HRH3 (0.45) | KDM4EMEN1KMT2AALDH1A1BCHE | |
| SCHEMBL3380644 | 0.81 | ALDH1A1 (0.39) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3380460 | 0.80 | KCNH2 (0.45) | KDM4EMEN1KMT2AMAPTBCHE | |
| SCHEMBL3380792 | 0.80 | HRH3 (0.39) | KDM4EALDH1A1BCHE | |
| SCHEMBL3377352 | 0.79 | HRH3 (0.51) | KMT2ABCHE | |
| Hydrochloric Acid SCHEMBL3378364 | 0.78 | HRH3 (0.41) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3378366 | 0.78 | HRH3 (0.41) | KDM4ETSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |