Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21899485 | 0.82 | CYP3A4 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2732615 | 0.81 | TSHR (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19CLK4 | |
| SCHEMBL22232393 | 0.80 | ADRB2 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1586204 | 0.78 | CLK4 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19CLK4 | |
| SCHEMBL29912400 | 0.78 | CLK4 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19CLK4 | |
| SCHEMBL11963779 | 0.76 | GRM5 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19MAP2K1 | |
| SCHEMBL1848389 | 0.75 | PDPK1 (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19HDAC1 | |
| SCHEMBL3377900 | 0.74 | CLK4 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19CLK4 | |
| SCHEMBL27510138 | 0.73 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3259923 | 0.73 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9427400-B2 | Platinum-catalyzed intravaginal rings | INTERNATIONAL PARTNERSHIP FOR MICROBICIDES (US) | 2016-08-30 | — | — | US | disclosed |
| US-20140056961-A1 | PLATINUM-CATALYZED INTRAVAGINAL RINGS | INTERNATIONAL PARTNERSHIP FOR MICROBICIDES (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2010038081-A2 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140056961-A1 | PLATINUM-CATALYZED INTRAVAGINAL RINGS | PCNA, DPYD, QDPR | CYP1A2 719/4885CYP3A4 287/4885CYP2C9 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.