Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14941708 | 0.86 | MAP2K1 (0.36) | GSK3BDYRK1AMAP2K1NFATC1CYP1A2 | |
| SCHEMBL6131063 | 0.80 | ESR2 (0.47) | CLK4CYP1A2CYP3A4CYP11B2LRRK2 | |
| SCHEMBL21596836 | 0.78 | LRRK2 (0.43) | CLK4NISCHHTTCYP11B2LRRK2 | |
| SCHEMBL3259928 | 0.76 | ESR2 (0.47) | MAP2K1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11963778 | 0.75 | GRM5 (0.43) | GSK3BDYRK1AMAP2K1NFATC1CYP1A2 | |
| SCHEMBL2423501 | 0.75 | TSHR (0.46) | MAP2K1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3377895 | 0.74 | CYP1A2 (0.41) | CLK4GSK3BDYRK1AMAP2K1CYP1A2 | |
| SCHEMBL27693511 | 0.73 | ESR2 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19LRRK2 | |
| SCHEMBL20240079 | 0.73 | KDM4E (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL27930441 | 0.72 | ESR2 (0.47) | MAP2K1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9427400-B2 | Platinum-catalyzed intravaginal rings | INTERNATIONAL PARTNERSHIP FOR MICROBICIDES (US) | 2016-08-30 | — | — | US | disclosed |
| US-20140056961-A1 | PLATINUM-CATALYZED INTRAVAGINAL RINGS | INTERNATIONAL PARTNERSHIP FOR MICROBICIDES (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2010038081-A2 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140056961-A1 | PLATINUM-CATALYZED INTRAVAGINAL RINGS | PCNA, DPYD, QDPR | CLK4 1722/4885GSK3B 3112/4885DYRK1A 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.