SCHEMBL6131063

SCHEMBL6131063

N#Cc1ccccc1-c1ncccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.47
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRA3 P34903 2/20 0.42
GABRA1 P14867 1/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
USP2 O75604 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PTGES O14684 1/20 0.41
TSHR P16473 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
GABRA5 P31644 1/20 0.41
GRIA1 P42261 1/20 0.40
GRIA3 P42263 1/20 0.40
PDE4D Q08499 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8359938 0.83 ESR2 (0.44) ESR2GABRG2GABRB3GABRA3GABRA1
SCHEMBL2478854 0.82 ESR2 (0.50) ESR2GABRG2GABRB3GABRA3GABRA1
SCHEMBL3377900 0.80 CLK4 (0.41) ESR2ALDH1A1HPGDMEN1KMT2A
SCHEMBL26337264 0.80 TSHR (0.45) ESR2GABRG2GABRB3GABRA3GABRA1
SCHEMBL21596836 0.80 LRRK2 (0.43) GABRG2GABRB3GABRA3GABRA1CLK4
SCHEMBL16148932 0.80 ALOX5AP (0.43) ESR2GABRG2GABRB3GABRA3GABRA1
SCHEMBL2651123 0.80 ESR2 (0.39) ESR2GABRG2GABRB3GABRA3GABRA1
SCHEMBL27999979 0.80 GABRA1 (0.44) ESR2GABRG2GABRB3GABRA3GABRA1
SCHEMBL973015 0.79 GRIA1 (0.51) ESR2GABRG2GABRB3GABRA3ALDH1A1
SCHEMBL31070227 0.79 GRIA1 (0.51) ESR2GABRG2GABRB3GABRA3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1194638-A Substituted cyanophenyl uracils BAYER AG (DE) 1998-09-30 CN claimed
US-5454975-A Electrooptical display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-10-03 US claimed
EP-0032397-A1 Method of manufacturing a liquid crystal display SIEMENS AKTIENGESELLSCHAFT (DE) 1981-07-22 EP claimed
JP-2282718-A None JP disclosed
US-20260036861-A1 LIQUID CRYSTAL ELEMENT, DISPLAY DEVICE, AND DIMMER DEVICE MURATA MANUFACTURING CO (JP) 2026-02-05 US disclosed
US-20250304857-A1 AROMATIC AMINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, DISPLAY APPARATUS, AND LIGHT CONTROL APPARATUS MURATA MANUFACTURING CO., LTD. (JP) 2025-10-02 US disclosed
WO-2025023061-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, DISPLAY DEVICE, AND DIMMING DEVICE 株式会社村田製作所 2025-01-30 WO disclosed
WO-2024219259-A1 LIQUID CRYSTAL ELEMENT, DISPLAY DEVICE, AND LIGHT CONTROL DEVICE 株式会社村田製作所 2024-10-24 WO disclosed
WO-2024096003-A1 AROMATIC AMINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, DISPLAY DEVICE, AND LIGHT MODULATION DEVICE 株式会社村田製作所 2024-05-10 WO disclosed
CN-106566561-A Preparation method of cyanophenyl pyrimidine type liquid crystal monomer 中节能万润股份有限公司 2017-04-19 CN disclosed
CN-106566561-A Preparation method of cyanophenyl pyrimidine type liquid crystal monomer 中节能万润股份有限公司 2017-04-19 CN disclosed
EP-0108472-A2 Organic materials for a liquid crystal device The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1984-05-16 EP disclosed
EP-0092682-A1 Lubricant ASULAB S.A. (CH) 1983-11-02 EP disclosed
EP-0091226-A2 Dielectric materials The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1983-10-12 EP disclosed
US-4405211-A CLOCKS; DISPLAYING; OPTICAL APPARATUS; ELECTRICAL THIN FILMS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1983-09-20 US disclosed
US-4391489-A Liquid crystal materials containing pleochroic anthraquinone dyes THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1983-07-05 US disclosed
US-4370028-A Method of producing liquid crystal display devices with alignment layer formed from organic tin compound of the type Rn SnX4-n SIEMENS AKTIENGESELLSCHAFT (DE) 1983-01-25 US disclosed
EP-0059095-A1 Liquid crystal materials comprising pleochroic dyes The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1982-09-01 EP disclosed
EP-0049035-A1 Organic compositions suitable for a guest-host liquid crystal device The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1982-04-07 EP disclosed
EP-0049036-A1 Organic compositions suitable for guest-host liquid crystal device The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1982-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304857-A1 AROMATIC AMINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, DISPLAY APPARATUS, AND LIGHT CONTROL APPARATUS C1S, AAAS, ATR ESR2 3341/4885GABRG2 4231/4885GABRB3 4683/4885
US-20260036861-A1 LIQUID CRYSTAL ELEMENT, DISPLAY DEVICE, AND DIMMER DEVICE DVL1, DVL3, DLK1 ESR2 1220/4885GABRG2 3716/4885GABRB3 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.