Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378457 | 1.00 | LMNA (0.51) | LMNAPKMRNPEPALDH1A1RAB9A | |
| SCHEMBL8770803 | 0.83 | LMNA (0.41) | LMNAPKMRNPEPALDH1A1RAB9A | |
| SCHEMBL15459572 | 0.83 | LMNA (0.41) | LMNAPKMRNPEPALDH1A1RAB9A | |
| SCHEMBL29456085 | 0.83 | RNPEP (0.54) | LMNAPKMRNPEPALDH1A1NPSR1 | |
| SCHEMBL8928051 | 0.83 | RNPEP (0.54) | LMNAPKMRNPEPALDH1A1RAB9A | |
| SCHEMBL164056 | 0.81 | RNPEP (0.52) | LMNAPKMRNPEPALDH1A1RAB9A | |
| SCHEMBL748892 | 0.81 | RNPEP (0.52) | LMNAPKMRNPEPALDH1A1RAB9A | |
| SCHEMBL1110748 | 0.81 | RNPEP (0.52) | LMNAPKMRNPEPALDH1A1NPSR1 | |
| SCHEMBL30975661 | 0.81 | RNPEP (0.52) | LMNAPKMRNPEPALDH1A1RAB9A | |
| SCHEMBL76427 | 0.81 | RNPEP (0.52) | LMNAPKMRNPEPALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | claimed |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | HELLER ADAM | 2008-11-20 | — | — | US | claimed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | claimed |
| JP-2930723-B2 | — | — | 1999-08-03 | — | — | JP | claimed |
| US-5690929-A | Use of methioninase and chemotherapy agents in chemotherapy | ANTICANCER, INC. (US) | 1997-11-25 | — | — | US | claimed |
| EP-0668933-A4 | USE OF METHIONINASE AS AN ANTITUMOR AGENT IN ANTI-METHIONINE CHEMOTHERAPY. | ANTICANCER INC (US) | 1997-05-21 | — | — | EP | claimed |
| EP-0668933-A1 | USE OF METHIONINASE AS AN ANTITUMOR AGENT IN ANTI-METHIONINE CHEMOTHERAPY | ANTICANCER, INC. (US) | 1995-08-30 | — | — | EP | claimed |
| WO-1994011535-A1 | USE OF METHIONINASE AS AN ANTITUMOR AGENT IN ANTI-METHIONINE CHEMOTHERAPY | ANTICANCER, INC. (US) | 1994-05-26 | — | — | WO | claimed |
| EP-0250583-A1 | USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS | A. Nattermann & Cie. GmbH (DE) | 1988-01-07 | — | — | EP | claimed |
| EP-0231765-A1 | Use of membrane modulators and products comprising such membrane modulators | A. Nattermann & Cie. GmbH (DE) | 1987-08-12 | — | — | EP | claimed |
| WO-1987004048-A1 | USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS | A. NATTERMANN & CIE GMBH (DE) | 1987-07-16 | — | — | WO | claimed |
| US-3991107-A | Haloamine transfer | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1976-11-09 | — | — | US | claimed |
| US-20240091121-A1 | PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL | O.Y.M. INNOVATION LTD. (IL) | 2024-03-21 | — | — | US | disclosed |
| EP-4274539-A2 | PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL | O.Y.M. Innovation Ltd. (IL) | 2023-11-15 | — | — | EP | disclosed |
| CN-116710046-A | Phosphonic acid and N-halamine compositions for tartar removal | O.Y.M.创新有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2022149126-A2 | PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL | O.Y.M. INNOVATION LTD. (IL) | 2022-07-14 | — | — | WO | disclosed |
| EP-0668933-A1 | USE OF METHIONINASE AS AN ANTITUMOR AGENT IN ANTI-METHIONINE CHEMOTHERAPY | ANTICANCER, INC. (US) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011535-A1 | USE OF METHIONINASE AS AN ANTITUMOR AGENT IN ANTI-METHIONINE CHEMOTHERAPY | ANTICANCER, INC. (US) | 1994-05-26 | — | — | WO | disclosed |
| US-3991107-A | Haloamine transfer | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |
| US-3943628-A | Spoon excavator for applying chemically acting tooth decay attacking fluid | KRONMAN JOSEPH H | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240091121-A1 | PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL | PHOSPHO1, PHPT1, PTMS | LMNA 1066/4885PKM 3136/4885RNPEP 868/4885 |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | ACHE, S100P, P2RX3 | LMNA 1174/4885PKM 2873/4885RNPEP 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.