Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 19/20 | 0.49 |
| ▸ | PROKR1 | Q8TCW9 | 19/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377172 | 0.88 | FPR2 (0.46) | FPR2PROKR1HRH3 | |
| SCHEMBL3379142 | 0.85 | HRH3 (0.41) | FPR2PROKR1HRH3 | |
| SCHEMBL3380067 | 0.84 | FPR2 (0.39) | FPR2PROKR1 | |
| SCHEMBL3377923 | 0.83 | HRH3 (0.43) | HRH3 | |
| SCHEMBL3377335 | 0.82 | HRH3 (0.48) | HRH3 | |
| SCHEMBL3378015 | 0.82 | HRH3 (0.45) | HRH3 | |
| SCHEMBL3378079 | 0.81 | HRH3 (0.48) | HRH3 | |
| SCHEMBL3375325 | 0.81 | HRH3 (0.43) | HRH3 | |
| SCHEMBL3376046 | 0.81 | HRH3 (0.44) | HRH3 | |
| SCHEMBL3380045 | 0.81 | HRH3 (0.44) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |