Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 16/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 16/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381234 | 0.94 | FPR2 (0.39) | FPR2PROKR1NMT1ALDH1A1 | |
| SCHEMBL3376186 | 0.86 | TSHR (0.36) | ALDH1A1LMNANPSR1 | |
| SCHEMBL3377307 | 0.85 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL3378561 | 0.84 | FPR2 (0.49) | FPR2PROKR1 | |
| SCHEMBL3377172 | 0.83 | FPR2 (0.46) | FPR2PROKR1ALDH1A1GAA | |
| SCHEMBL3376674 | 0.83 | CXCR4 (0.41) | ALDH1A1GAALMNA | |
| SCHEMBL3380056 | 0.83 | CXCR4 (0.45) | ALDH1A1 | |
| SCHEMBL3380637 | 0.82 | ACKR3 (0.35) | ALDH1A1 | |
| SCHEMBL3376045 | 0.82 | KDM4E (0.41) | ALDH1A1 | |
| SCHEMBL3379302 | 0.82 | CXCR4 (0.42) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |