Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278948 | 0.65 | — | — | |
| SCHEMBL11344971 | 0.64 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL27521711 | 0.62 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL28212613 | 0.61 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL28874686 | 0.61 | KDM4E (0.40) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL11180935 | 0.60 | KDM4E (0.54) | KDM4EALDH1A1HPGDMEN1MAPT | |
| Bromide SCHEMBL11132876 | 0.60 | KDM4E (0.39) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL7604374 | 0.58 | KDM4E (0.33) | KDM4EALDH1A1HPGDMEN1MAPT | |
| Hydrochloric Acid SCHEMBL28174881 | 0.57 | KDM4E (0.33) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL28020567 | 0.55 | KDM4E (0.34) | KDM4EALDH1A1HPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049678-A2 | TREATMENT OF ENERGY UTILIZATION DISEASES | SUMMIT CORPORATION PLC (GB) | 2010-05-06 | — | — | WO | disclosed |