SCHEMBL3379180

SCHEMBL3379180

NC(Cl)(CCC(=O)O)P(=O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
THRB P10828 1/20 0.41
FDPS P14324 6/20 0.40
SMPD1 P17405 2/20 0.35
FOLH1 Q04609 4/20 0.33
LMNA P02545 3/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
GRM8 O00222 1/20 0.32
GRM6 O15303 1/20 0.32
GRM7 Q14831 1/20 0.32
GRM4 Q14833 1/20 0.32
ADRB3 P13945 1/20 0.32
PDE4D Q08499 1/20 0.32
PDE3A Q14432 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10324944 0.74 ALDH1A1 (0.45) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL20533249 0.74 ALDH1A1 (0.45) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL7635329 0.74
SCHEMBL2717818 0.72 GGPS1 (0.43) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL19043007 0.70 FDPS (0.52) FDPSFOLH1LMNAALKBH5SUCNR1
SCHEMBL9495952 0.68 MEN1 (0.39) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL11222977 0.68 MEN1 (0.39) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL9639348 0.68 MEN1 (0.39) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL22514 0.68 ALDH1A1 (0.35) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL1868226 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101132785-A N-halogenated amino acids and N, N-dihalogenated amino acids in combination with hypohalous acids NOVABAY PHARMACEUTICALS INC (US) 2008-02-27 CN claimed
CN-1902158-B N,N-dihalogenated amino acids and derivatives NOVACAL PHARMACEUTICALS INC 2011-04-06 CN disclosed
WO-2010017405-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN HELLER ADAM (US) 2010-02-11 WO disclosed
CN-101132785-A N-halogenated amino acids and N, N-dihalogenated amino acids in combination with hypohalous acids NOVABAY PHARMACEUTICALS INC (US) 2008-02-27 CN disclosed
CN-1902158-A N,N-dihalogenated amino acids and derivatives NOVACAL PHARMACEUTICALS INC (US) 2007-01-24 CN disclosed