Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040704 | 0.85 | LMNA (0.46) | MEN1KMT2AALDH1A1LMNAFOLH1 | |
| SCHEMBL9639348 | 0.76 | MEN1 (0.39) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL21611881 | 0.76 | FDPS (0.50) | — | |
| SCHEMBL11353091 | 0.76 | GRM4 (0.43) | MEN1KMT2AALDH1A1LMNAFOLH1 | |
| SCHEMBL9495952 | 0.76 | MEN1 (0.39) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL2717818 | 0.75 | GGPS1 (0.43) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL19043007 | 0.73 | FDPS (0.52) | LMNAALKBH5SUCNR1EGLN1FOLH1 | |
| SCHEMBL7111437 | 0.73 | NAALAD2 (0.44) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL22514 | 0.71 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL12473686 | 0.70 | FDPS (0.37) | MEN1KMT2AALDH1A1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320025-A | Cavitation-inhibiting, nonfreezing, cooling and/or heat transfer fluids | CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DE) | 1982-03-16 | — | — | US | disclosed |