SCHEMBL337976

SCHEMBL337976

Brc1ccc(-n2c(-c3ccccn3)nc3ccccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.47
ESR1 P03372 2/20 0.47
CTSD P07339 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HRH3 Q9Y5N1 7/20 0.45
DHFR P00374 1/20 0.44
HTT P42858 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KCNH2 Q12809 2/20 0.43
MAPK1 P28482 1/20 0.43
GRIA1 P42261 1/20 0.43
CACNG8 Q8WXS5 1/20 0.43
CACNG2 Q9Y698 1/20 0.43
GUSB P08236 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30172357 0.93 ESR2 (0.53) ESR2ESR1CTSDL3MBTL1HRH3
SCHEMBL13376084 0.88 HTT (0.56) ESR2ESR1CTSDL3MBTL1HRH3
SCHEMBL18221927 0.87 CTSD (0.45) CTSDL3MBTL1HRH3DHFRHTT
SCHEMBL24953014 0.86 CTSD (0.56) ESR2ESR1CTSDL3MBTL1HRH3
SCHEMBL29470569 0.85 CTSD (0.50) ESR2ESR1CTSDL3MBTL1HRH3
SCHEMBL30530929 0.85 CTSD (0.50) ESR2ESR1CTSDL3MBTL1HRH3
SCHEMBL18221919 0.85 DHFR (0.44) CTSDL3MBTL1HRH3DHFRHTT
SCHEMBL338229 0.83 HRH3 (0.48) HRH3DHFRKCNH2
SCHEMBL24953176 0.81 CTSD (0.55) ESR2ESR1CTSDL3MBTL1HRH3
SCHEMBL24953175 0.81 CTSD (0.55) ESR2ESR1CTSDL3MBTL1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602648-B2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO (JP) 2025-03-26 EP disclosed
EP-3259786-B1 SEMICONDUCTING MATERIAL AND NAPHTOFURANE MATRIX COMPOUND FOR IT NOVALED GMBH (DE) 2023-08-30 EP disclosed
US-11362285-B2 Semiconducting material and naphthofurane matrix compound for it NOVALED GMBH (DE) 2022-06-14 US disclosed
EP-3294727-B1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2021-08-04 EP disclosed
EP-3294727-B1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER NOVALED GMBH (DE) 2021-08-04 EP disclosed
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer NOVALED GMBH (DE) 2021-08-03 US disclosed
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer NOVALED GMBH (DE) 2021-08-03 US disclosed
CN-107750404-B Organic light emitting diode comprising different host compounds in first and second electron transport layers 诺瓦尔德股份有限公司 2021-06-04 CN disclosed
US-20200280002-A1 Semiconducting Material and Naphthofurane Matrix Compound for It NOVALED GMBH (DE) 2020-09-03 US disclosed
US-10658599-B2 Semiconducting material and naphthofurane matrix compound for it NOVALED GMBH (DE) 2020-05-19 US disclosed
EP-3093288-A1 ORGANIC LIGHT-EMITTING DIODE COMPRISING DIFFERENT MATRIX COMPOUNDS IN THE FIRST AND SECOND ELECTRON TRANSPORT LAYER Novaled GmbH (DE) 2016-11-16 EP disclosed
WO-2016131918-A1 SEMICONDUCTING MATERIAL AND NAPHTOFURANE MATRIX COMPOUND FOR IT NOVALED GMBH (DE) 2016-08-25 WO disclosed
EP-1602648-B1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO (JP) 2013-04-17 EP disclosed
US-8097349-B2 Nitrogen containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-01-17 US disclosed
US-7851071-B2 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2010-12-14 US disclosed
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD, (JP) 2010-08-05 US disclosed
EP-2174932-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-2174933-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
US-20060147747-A1 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed
EP-1602648-A1 NITROGEN-CONTAINING HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200280002-A1 Semiconducting Material and Naphthofurane Matrix Compound for It NES, NQO1, VIM ESR2 2583/4885ESR1 2176/4885CTSD 1707/4885
US-10658599-B2 Semiconducting material and naphthofurane matrix compound for it NES, NQO1, VIM ESR2 2583/4885ESR1 2176/4885CTSD 1707/4885
US-11362285-B2 Semiconducting material and naphthofurane matrix compound for it NES, NQO1, VIM ESR2 2583/4885ESR1 2176/4885CTSD 1707/4885
US-11081652-B2 Organic light-emitting diode comprising different matrix compounds in the first and second electron transport layer CYBA, CLTB, MAP1LC3B ESR2 397/4885ESR1 484/4885CTSD 226/4885
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same NSD1, EED, ERG ESR2 489/4885ESR1 77/4885CTSD 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.