SCHEMBL3379931

SCHEMBL3379931

NS(=O)(=O)Oc1ccccc1Br

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.50
CA1 P00915 12/20 0.50
CA9 Q16790 12/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.41
STS P08842 3/20 0.40
CYP19A1 P11511 1/20 0.40
HTR7 P34969 1/20 0.40
CA12 O43570 1/20 0.39
CA3 P07451 1/20 0.39
CA7 P43166 1/20 0.39
PLA2G7 Q13093 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
PLCG1 P19174 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9451267 0.84 CA2 (0.61) CA2CA1CA9STS
SCHEMBL4609029 0.78 CA1 (0.40) CA2CA1CA4CA6HTR7
SCHEMBL4313964 0.78 SLC22A6 (0.46) CA2CA1CA4CA6HTR7
SCHEMBL31444250 0.78 ELANE (0.59) CA2CA1CA9CA4CA6
SCHEMBL4667779 0.76 CA2 (0.56) CA2CA1CA9STSCYP19A1
SCHEMBL2785965 0.76 CA2 (0.52) CA2CA1CA9CA4CA6
SCHEMBL1075941 0.76 CA1 (0.52) CA2CA1CA9STSCA12
Ethane SCHEMBL28924785 0.75 SLC22A6 (0.43) CA2CA1CA4CA6CA5A
SCHEMBL27428843 0.75 ALDH1A1 (0.58) CA2CA1CA9CA4CA6
SCHEMBL9451230 0.74 CA2 (0.56) CA2CA1CA9CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010017405-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN HELLER ADAM (US) 2010-02-11 WO disclosed