Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.56 |
| ▸ | CA9 | Q16790 | 12/20 | 0.56 |
| ▸ | CA1 | P00915 | 11/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | STS | P08842 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667168 | 0.80 | CA2 (0.56) | CA2CA9CA1CA12STS | |
| SCHEMBL4667783 | 0.80 | CA1 (0.56) | CA2CA9CA1CA12STS | |
| SCHEMBL3379931 | 0.76 | CA2 (0.50) | CA2CA9CA1CA12STS | |
| SCHEMBL3924409 | 0.73 | MAPT (0.57) | NPC1LMNAMAPTTHRBRAB9A | |
| SCHEMBL7785330 | 0.72 | EPAS1 (0.39) | CA2CA1 | |
| SCHEMBL7263619 | 0.72 | CA2 (1.00) | CA2CA9CA1CA12STS | |
| Water SCHEMBL8845490 | 0.72 | MAPT (0.56) | NPC1LMNAMAPTTHRBRAB9A | |
| SCHEMBL9451359 | 0.72 | CA2 (0.70) | CA2CA9CA1CA12STS | |
| SCHEMBL2591595 | 0.70 | CA2 (0.68) | CA2CA9CA1CA12STS | |
| SCHEMBL10864194 | 0.70 | PKM (0.58) | CA2CA9CA1CA12WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |