Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684548 | 0.84 | TSHR (0.42) | KMT2AHTTMEN1LMNAL3MBTL1 | |
| SCHEMBL1291091 | 0.78 | KEAP1 (0.55) | KMT2AHTTL3MBTL1 | |
| SCHEMBL29388997 | 0.78 | KEAP1 (0.55) | KMT2AHTTL3MBTL1 | |
| SCHEMBL27182654 | 0.77 | POLB (0.44) | MCL1KMT2AHTTMEN1NPC1 | |
| Sulfuric Acid SCHEMBL20984747 | 0.77 | CA1 (0.53) | KMT2AHTTMEN1NPC1LMNA | |
| SCHEMBL1075937 | 0.76 | GAA (0.55) | KMT2AHTTMEN1NPC1LMNA | |
| SCHEMBL5731180 | 0.75 | ALDH1A1 (0.58) | KMT2AHTTMEN1CA1CA2 | |
| Sulfuric Acid SCHEMBL28200149 | 0.75 | KMT2A (0.42) | KMT2AHTTMEN1NPC1LMNA | |
| SCHEMBL1290833 | 0.75 | PSIP1 (0.61) | MCL1HTTLMNAPOLBTP53 | |
| SCHEMBL14295192 | 0.75 | POLB (0.40) | MCL1KMT2AHTTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |