Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307403 | 0.88 | ALDH1A1 (0.55) | POLBRAB9AKMT2AALDH1A1ATM | |
| SCHEMBL289605 | 0.82 | POLB (0.74) | POLBRAB9AKMT2AALDH1A1GFER | |
| SCHEMBL3849918 | 0.80 | POLB (1.00) | POLBRAB9AKMT2AALDH1A1KDM4E | |
| Hydrazine SCHEMBL27559974 | 0.80 | ALDH1A1 (0.72) | RAB9AKMT2AALDH1A1ATMGPR84 | |
| SCHEMBL64182 | 0.80 | GPR84 (0.77) | RAB9AKMT2AALDH1A1ATMGPR84 | |
| SCHEMBL29272694 | 0.78 | GPR84 (0.74) | RAB9AKMT2AALDH1A1ATMGPR84 | |
| SCHEMBL27837528 | 0.78 | GPR84 (0.74) | RAB9AKMT2AALDH1A1ATMGPR84 | |
| Hydrochloric Acid SCHEMBL7437913 | 0.78 | GPR84 (0.74) | RAB9AKMT2AALDH1A1ATMGPR84 | |
| Ammonia Solution, Strong SCHEMBL27380523 | 0.78 | GPR84 (0.74) | RAB9AKMT2AALDH1A1ATMGPR84 | |
| Hydrochloric Acid SCHEMBL29435427 | 0.78 | GPR84 (0.74) | RAB9AKMT2AALDH1A1ATMGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931680-B1 | INDOL-3-YL-CARBONYL-AZASPIRO DERIVATIVES AS VASOPRESSIN RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-11-17 | — | — | EP | disclosed |
| WO-2002094842-A2 | CONTROL OF MYOGENESIS BY MODULATION OF P38 MAP KINASE ACTIVITY | UNIVERSITY OF WESTERN ONTARIO (CA) | 2002-11-28 | — | — | WO | disclosed |