Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867891 | 0.86 | MAPT (0.35) | MAPT | |
| SCHEMBL16012061 | 0.81 | MAPT (0.37) | MAPTCYP1A2 | |
| SCHEMBL2897172 | 0.78 | CHRM5 (0.41) | MAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL13025301 | 0.78 | CHRM5 (0.41) | MAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL2897176 | 0.78 | CHRM5 (0.41) | MAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL2691391 | 0.78 | — | — | |
| SCHEMBL12172484 | 0.78 | TSHR (0.40) | CYP1A2SMN1; SMN2TSHR | |
| SCHEMBL7082613 | 0.74 | MAPT (0.60) | MAPTCYP1A2SMN1; SMN2SORT1MME | |
| SCHEMBL8507193 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2TSHRMME | |
| SCHEMBL5870408 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2TSHRMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120084903-A | Method for detecting related substances in 3-isobutyl glutaric anhydride | 河北圣雪大成制药有限责任公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120037202-A | Lipid nanoparticle based on cationic lipid with branched structure at junction and application of lipid nanoparticle | 浙江大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119108620-A | Method for assembling lithium battery by polymer electrolyte | 浙江大学 | 2024-12-10 | — | — | CN | claimed |
| CN-119081040-A | Preparation method of chemically recyclable polyacetal and product and chemical recycling method thereof | 浙江大学 | 2024-12-06 | — | — | CN | claimed |
| CN-118702912-A | Preparation method of spontaneously degradable cyclic poly (ester-peptide), product and degradation method thereof | 浙江大学 | 2024-09-27 | — | — | CN | claimed |
| CN-118125600-B | Composite carbon source for removing nitrogen component in wastewater and preparation method thereof | 广州市豫泉净水材料有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-118406203-A | Preparation method of intrinsic flame-retardant high-strength polyacetal and product thereof | 浙江大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118271586-A | Method for synthesizing polyester by ionic liquid catalysis | 福州大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118271570-A | Preparation method of organic phosphine-terminated non-conjugated oxygen-enriched fluorescent polymer, and product and application thereof | 浙江大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118125600-A | Composite carbon source for removing nitrogen component in wastewater and preparation method thereof | 广州市豫泉净水材料有限公司 | 2024-06-04 | — | — | CN | claimed |
| US-20080051602-A1 | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin | KANSAL VINOD K | 2008-02-28 | — | — | US | claimed |
| US-20080045747-A1 | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-pregabalin | KANSAL VINOD K | 2008-02-21 | — | — | US | claimed |
| US-20070293694-A1 | Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-12-20 | — | — | US | claimed |
| WO-2007139933-A2 | PROCESSES FOR THE PREPARATION OF R-(+)-3-(CARBAMOYL METHYL)-5-METHYLHEXANOIC ACID AND SALTS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-12-06 | — | — | WO | claimed |
| EP-1841726-A1 | AN ASYMMETRIC SYNTHESIS OF ( S ) - ( + ) -3- (AMINOMETHYL) -5-METHYLHEXANOIC ACID | Teva Pharmaceutical Industries Ltd (IL) | 2007-10-10 | — | — | EP | claimed |
| US-20070197827-A1 | Novel asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-08-23 | — | — | US | claimed |
| US-20070191636-A1 | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin | TEVA PHARMACEUTICAL USA, INC. | 2007-08-16 | — | — | US | claimed |
| EP-1802568-A1 | CHIRAL 3-CARBAMOYLMETHYL-5-METHYL HEXANOIC ACIDS, KEY INTERMEDIATES FOR THE NEW SYNTHESIS OF (S)-PREGABALIN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-07-04 | — | — | EP | claimed |
| WO-2007035890-A1 | AN ASYMMETRIC SYNTHESIS OF ( S ) - ( + ) -3- (AMINOMETHYL) -5-METHYLHEXANOIC ACID | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-03-29 | — | — | WO | claimed |
| WO-2007035789-A1 | CHIRAL 3-CARBAMOYLMETHYL-5-METHYL HEXANOIC ACIDS, KEY INTERMEDIATES FOR THE NEW SYNTHESIS OF (S)-PREGABALIN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-03-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197827-A1 | Novel asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid | RIMKLA, COASY, GABRE | MAPT 2162/4885CYP1A2 447/4885SMN1; SMN2 3043/4885 |
| US-20080045747-A1 | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-pregabalin | GABRE, GABRA5, GABRA6 | MAPT 1546/4885CYP1A2 624/4885SMN1; SMN2 2803/4885 |
| US-20070293694-A1 | Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof | RIMKLA, GABRE, GRIK5 | MAPT 1937/4885CYP1A2 966/4885SMN1; SMN2 2850/4885 |
| US-20080051602-A1 | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin | GABRE, GABRA5, GABRA6 | MAPT 1546/4885CYP1A2 624/4885SMN1; SMN2 2803/4885 |
| US-20070191636-A1 | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin | GABRE, GABRA5, GABRA6 | MAPT 1546/4885CYP1A2 624/4885SMN1; SMN2 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.