Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.51 |
| ▸ | DPYD | Q12882 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.46 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.45 |
| ▸ | TUBB | P07437 | 8/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380424 | 1.00 | KDM4E (0.53) | KDM4ECA12PARP1CA9IP6K1 | |
| SCHEMBL7022550 | 0.82 | PARP1 (0.46) | KDM4ECA12PARP1CA9IP6K1 | |
| SCHEMBL7022549 | 0.82 | PARP1 (0.46) | KDM4ECA12PARP1CA9IP6K1 | |
| SCHEMBL3373983 | 0.80 | KIF11 (0.56) | KDM4ECA12PARP1CA9RAB9A | |
| SCHEMBL7024202 | 0.78 | PARP1 (0.42) | KDM4ECA12PARP1CA9IP6K1 | |
| SCHEMBL7024197 | 0.78 | PARP1 (0.42) | KDM4ECA12PARP1CA9IP6K1 | |
| SCHEMBL7033757 | 0.78 | TYMP (0.43) | KDM4ECA12PARP1CA9IP6K1 | |
| SCHEMBL7033759 | 0.78 | TYMP (0.43) | KDM4ECA12PARP1CA9IP6K1 | |
| SCHEMBL7029179 | 0.78 | PARP1 (0.48) | KDM4ECA12PARP1CA9DPYD | |
| SCHEMBL7027670 | 0.76 | TYMP (0.46) | KDM4ECA12PARP1CA9IP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |