Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380494 | 1.00 | RORC (0.38) | RORCKDM4EALDH1A1TDP1BCHE | |
| SCHEMBL3379338 | 0.82 | HRH3 (0.38) | KDM4EALDH1A1BCHEACHEMAOB | |
| SCHEMBL3379341 | 0.82 | HRH3 (0.38) | KDM4EALDH1A1BCHEACHEMAOB | |
| SCHEMBL3377217 | 0.82 | NCF1 (0.37) | RORCKDM4EALDH1A1TDP1POLB | |
| SCHEMBL3377214 | 0.82 | NCF1 (0.37) | RORCKDM4EALDH1A1TDP1POLB | |
| SCHEMBL3442334 | 0.80 | RORC (0.37) | RORCKDM4EALDH1A1TDP1BCHE | |
| SCHEMBL3377533 | 0.80 | RORC (0.35) | RORCKDM4EALDH1A1TDP1ACHE | |
| SCHEMBL3442329 | 0.78 | HRH3 (0.45) | RORCKDM4EALDH1A1TDP1BCHE | |
| SCHEMBL3442332 | 0.78 | HRH3 (0.45) | RORCKDM4EALDH1A1TDP1BCHE | |
| SCHEMBL3378184 | 0.78 | HRH3 (0.44) | RORCKDM4EALDH1A1TDP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | disclosed |