Sulfuric Acid

Sulfuric Acid

SCHEMBL3380495

O=S(=O)(O)O.c1ccc2c(c1)-c1ccccc1-2

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA known ✓ P21397 3/20 0.59
MAOB known ✓ P27338 1/20 0.40
MAP2K1 known ✓ Q02750 1/20 0.40
MAPT P10636 5/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
TDP2 O95551 3/20 0.59
S100A4 P26447 3/20 0.59
MAPK1 P28482 3/20 0.59
KDM4E B2RXH2 3/20 0.59
APAF1 O14727 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
PLA2G1B P04054 2/20 0.59
ATG4B Q9Y4P1 2/20 0.59
RECQL P46063 2/20 0.59
LMNA P02545 2/20 0.59
HTT P42858 2/20 0.59
CES2 O00748 1/20 0.59
TERT O14746 1/20 0.59
NPC1 O15118 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL2057392 0.97 MAPT (0.56) MAPTMEN1KMT2ATDP2S100A4
Anthraquinone SCHEMBL3895044 0.87 MEN1 (0.75) MAPTMEN1KMT2ATDP2S100A4
Anthraquinone SCHEMBL28860881 0.84 MEN1 (0.71) MAPTMEN1KMT2ATDP2S100A4
Anthraquinone SCHEMBL5348481 0.84 MEN1 (0.71) MAPTMEN1KMT2ATDP2S100A4
Sulfuric Acid SCHEMBL391429 0.80 SMN1; SMN2 (0.46) MAPTMEN1KMT2ATDP2S100A4
Naphthoquinone SCHEMBL27601003 0.80 IDO1 (0.74) MAPTMEN1KMT2ATDP2S100A4
Naphthalene SCHEMBL672294 0.79 ALOX12 (0.57) MAPTKDM4ESMN1; SMN2LMNACES2
Naphthalene SCHEMBL5574575 0.79 ALOX12 (0.57) MAPTKDM4ESMN1; SMN2LMNACES2
Sulfamide SCHEMBL9577223 0.79 MEN1 (0.59) MAPTMEN1KMT2ATDP2S100A4
Naphthalene SCHEMBL29361795 0.79 ALOX12 (0.57) MAPTKDM4ESMN1; SMN2LMNACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100155303-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2010-06-24 US disclosed
EP-1923451-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2008-05-21 EP disclosed