Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379754 | 0.88 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3378779 | 0.86 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL7928989 | 0.85 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3379679 | 0.80 | DHFR (0.38) | — | |
| SCHEMBL3380528 | 0.78 | PDE4D (0.60) | — | |
| SCHEMBL2918713 | 0.78 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3377728 | 0.78 | PDE4D (0.46) | — | |
| SCHEMBL3433258 | 0.76 | DPP4 (0.38) | — | |
| SCHEMBL3377566 | 0.74 | DYRK3 (0.50) | — | |
| SCHEMBL7916793 | 0.74 | DPP4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010059836-A1 | SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |