Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932127 | 0.89 | DYRK3 (0.51) | DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL3378779 | 0.86 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3380717 | 0.85 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3379754 | 0.85 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL7928993 | 0.80 | RAB9A (0.41) | — | |
| SCHEMBL2918713 | 0.78 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL7930902 | 0.76 | XPO1 (0.35) | DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL3377728 | 0.75 | PDE4D (0.46) | — | |
| SCHEMBL3377566 | 0.74 | DYRK3 (0.50) | DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL3378344 | 0.73 | ABL1 (0.39) | DYRK3DYRK1ADYRK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059836-A1 | SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |