Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879022 | 0.83 | MEN1 (0.50) | CXCL8ALDH1A1LMNASMN1; SMN2CXCR2 | |
| SCHEMBL15568879 | 0.83 | MEN1 (0.50) | CXCL8ALDH1A1LMNASMN1; SMN2CXCR2 | |
| SCHEMBL15568569 | 0.83 | MEN1 (0.50) | CXCL8ALDH1A1LMNASMN1; SMN2CXCR2 | |
| SCHEMBL1983999 | 0.83 | LMNA (0.47) | ALDH1A1LMNASMN1; SMN2ATML3MBTL1 | |
| SCHEMBL29430352 | 0.83 | LMNA (0.47) | ALDH1A1LMNASMN1; SMN2ATML3MBTL1 | |
| SCHEMBL3381057 | 0.83 | LMNA (0.47) | ALDH1A1LMNASMN1; SMN2ATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL28022283 | 0.81 | LMNA (0.46) | ALDH1A1LMNASMN1; SMN2ATML3MBTL1 | |
| SCHEMBL28581260 | 0.81 | RXFP1 (0.45) | ALDH1A1LMNASMN1; SMN2ATML3MBTL1 | |
| SCHEMBL2941689 | 0.76 | CXCL8 (0.50) | CXCL8ALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5022885 | 0.76 | CXCL8 (0.50) | CXCL8ALDH1A1LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |