Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983999 | 1.00 | LMNA (0.47) | LMNAKMT2AHTTRAB9AMEN1 | |
| SCHEMBL3381057 | 1.00 | LMNA (0.47) | LMNAKMT2AHTTRAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL28022283 | 0.98 | LMNA (0.46) | LMNAKMT2AHTTRAB9AMEN1 | |
| SCHEMBL28266875 | 0.84 | L3MBTL1 (0.46) | LMNAKMT2AHTTRAB9AMEN1 | |
| SCHEMBL28581260 | 0.83 | RXFP1 (0.45) | LMNAKMT2AMEN1L3MBTL1ATM | |
| SCHEMBL3380718 | 0.83 | CXCL8 (0.39) | LMNAKMT2AHTTRAB9AMEN1 | |
| SCHEMBL5323369 | 0.79 | HPGD (0.49) | LMNAKMT2AHTTRAB9AMEN1 | |
| SCHEMBL7200135 | 0.79 | RAB9A (0.52) | LMNAKMT2AHTTRAB9AMEN1 | |
| SCHEMBL5062929 | 0.79 | RAB9A (0.52) | LMNAKMT2AHTTRAB9AMEN1 | |
| SCHEMBL3078752 | 0.79 | RAB9A (0.52) | LMNAKMT2AHTTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966226-A1 | MASP INHIBITORY COMPOUNDS AND USES THEREOF | Bayer Aktiengesellschaft (DE) | 2022-03-16 | — | — | EP | disclosed |