Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154109 | 0.85 | KDM4E (0.35) | KDM4EAKR1B1GRM4ALDH1A1CA1 | |
| SCHEMBL3162480 | 0.84 | KDM4E (0.34) | KDM4EAKR1B1GRM4ALDH1A1CA1 | |
| SCHEMBL5290426 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CA1CA2 | |
| SCHEMBL5298836 | 0.80 | ALDH1A1 (0.39) | KDM4EAKR1B1ALDH1A1CA1CA2 | |
| SCHEMBL28729345 | 0.80 | — | — | |
| SCHEMBL5289822 | 0.78 | KDM4E (0.47) | KDM4EAKR1B1GRM4ALDH1A1 | |
| SCHEMBL14364508 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL13588831 | 0.73 | CA1 (0.31) | CA1CA2HSD11B1 | |
| SCHEMBL20870965 | 0.72 | NPSR1 (0.41) | ALDH1A1 | |
| SCHEMBL20870961 | 0.72 | PIK3CD (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186410-B1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-1364946-B1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7833939-B2 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-2186410-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-05-19 | — | — | EP | disclosed |
| US-7238689-B2 | Isoxazoline derivative and herbicide comprising the same as active ingredient | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| EP-1203768-B1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-20050256004-A1 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| US-6841519-B1 | Isoxazoline derivatives and herbicides containing the same as the active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-01-11 | — | — | US | disclosed |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| EP-1364946-A1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-11-26 | — | — | EP | disclosed |
| EP-1203768-A1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256004-A1 | Herbicide compositions | DDT, CYP4X1, GLRX3 | KDM4E 1984/4885AKR1B1 802/4885GRM4 124/4885 |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | CYP4X1, PRDX5, CYP3A7 | KDM4E 1263/4885AKR1B1 1581/4885GRM4 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.