Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IL2 | P60568 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3162480 | 0.99 | KDM4E (0.34) | KDM4EAKR1B1GRM4CA1CA2 | |
| SCHEMBL5289822 | 0.91 | KDM4E (0.47) | KDM4EAKR1B1GRM4ALDH1A1LMNA | |
| SCHEMBL14364508 | 0.87 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTHPGDMAPK1 | |
| SCHEMBL13588831 | 0.86 | CA1 (0.31) | CA1CA2HSD11B1IL2 | |
| SCHEMBL3380968 | 0.85 | KDM4E (0.33) | KDM4EAKR1B1GRM4CA1CA2 | |
| SCHEMBL13588898 | 0.84 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL13986674 | 0.83 | — | — | |
| SCHEMBL13588833 | 0.81 | — | — | |
| SCHEMBL20855344 | 0.81 | ALDH1A1 (0.42) | CA1CA2ALDH1A1LMNAMAPT | |
| SCHEMBL14364509 | 0.81 | OPRM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680290-B2 | Isoxazoline derivatives and their use as herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-8680290-B2 | Isoxazoline derivatives and their use as herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-8680290-B2 | Isoxazoline derivatives and their use as herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-8404618-B2 | Herbicidal composition | SYNGENTA LIMITED (GB) | 2013-03-26 | — | — | US | disclosed |
| US-8404618-B2 | Herbicidal composition | SYNGENTA LIMITED (GB) | 2013-03-26 | — | — | US | disclosed |
| EP-1789401-B1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2010-03-03 | — | — | EP | disclosed |
| EP-1789401-B1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2010-03-03 | — | — | EP | disclosed |
| US-20090042726-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042726-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042726-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20080139390-A1 | Isoxazoline Derivatives and Their Use as Herbicides | SYNGENTA LIMITED (GB) | 2008-06-12 | — | — | US | disclosed |
| EP-1755397-B1 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-09 | — | — | EP | disclosed |
| US-20070259786-A1 | Herbicidal Composition | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-08 | — | — | US | disclosed |
| US-20070259786-A1 | Herbicidal Composition | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-08 | — | — | US | disclosed |
| WO-2007071900-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |
| EP-1789401-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006024820-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2006-03-09 | — | — | WO | disclosed |
| EP-1203768-B1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-6841519-B1 | Isoxazoline derivatives and herbicides containing the same as the active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-01-11 | — | — | US | disclosed |
| EP-1203768-A1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259786-A1 | Herbicidal Composition | DDT, IDH2, ACHE | KDM4E 1547/4885AKR1B1 957/4885GRM4 866/4885 |
| US-20080139390-A1 | Isoxazoline Derivatives and Their Use as Herbicides | MTX1, MTX2, CHRM1 | KDM4E 1939/4885AKR1B1 622/4885GRM4 2743/4885 |
| US-20090042726-A1 | Novel Herbicides | DDT, CBR3, CBR1 | KDM4E 1271/4885AKR1B1 101/4885GRM4 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.