Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3385857 | 0.96 | SIGMAR1 (0.35) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL3383067 | 0.96 | SIGMAR1 (0.35) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Fluoride SCHEMBL3382394 | 0.96 | SIGMAR1 (0.35) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Iodide SCHEMBL3382542 | 0.80 | HTR2A (0.36) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL6324320 | 0.77 | HTR2A (0.40) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL4918618 | 0.77 | HTR2A (0.40) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL3383165 | 0.76 | HTR2A (0.36) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Bromide SCHEMBL3380480 | 0.76 | HTR2A (0.36) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Fluoride SCHEMBL3384859 | 0.76 | HTR2A (0.36) | SIGMAR1HTR2AHTR6KDM4EBRD4 | |
| Biphenyl SCHEMBL9278337 | 0.74 | ALDH1A1 (0.36) | SIGMAR1HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709586-B2 | Olefin polymerization catalyst and olefin polymerization process using the same | DAELIM INDUSTRIAL CO., LTD. (KR) | 2010-05-04 | — | — | US | disclosed |
| US-20070142221-A1 | Olefin polymerization catalyst and olefin polymerization process using the same | DAELIM INDUSTRIAL CO., LTD. | 2007-06-21 | — | — | US | disclosed |