SCHEMBL6324320

SCHEMBL6324320

C1=CC([Hf]C2C=Cc3ccccc32)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.40
HTR6 P50406 1/20 0.39
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 2/20 0.32
CYP2D6 P10635 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4918618 1.00 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Ethylene SCHEMBL6917299 0.96 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Biphenyl SCHEMBL9278337 0.92 ALDH1A1 (0.36) HTR2AHTR6SIGMAR1
SCHEMBL15189741 0.92 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL8779649 0.88 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL6917288 0.84 HTR2A (0.33) HTR2AHTR6KDM4ECYP2D6LMNA
SCHEMBL8779509 0.84 HTR6 (0.31) HTR2AHTR6
SCHEMBL8779540 0.82 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Hydrochloric Acid SCHEMBL3383165 0.80 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Bromide SCHEMBL3380480 0.80 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-01-20 US claimed
US-12503529-B2 Polymers of 4-substituted hexadiene and processes for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-12-23 US claimed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US claimed
EP-4192888-A1 METHODS FOR DELIVERY OF NON-AROMATIC SOLUTIONS TO POLYMERIZATION REACTORS ExxonMobil Chemical Patents Inc. (US) 2023-06-14 EP claimed
CN-116209683-A Method for delivering non-aromatic solutions to a polymerization reactor 埃克森美孚化学专利公司 2023-06-02 CN claimed
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US claimed
US-20220289879-A1 Polymers of 4-Substituted Hexadiene and Processes for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-09-15 US claimed
CN-110272356-A A kind of method of cyclododecanone oximate 万华化学集团股份有限公司 2019-09-24 CN claimed
EP-1910432-B1 PROCESS TO PRODUCE LOW VISCOSITY POLY-ALPHA-OLEFINS EXXONMOBIL CHEM PATENTS INC (US) 2014-11-12 EP claimed
EP-0588404-B1 Catalyst and process for polymerizing alpha-olefins ENICHEM SPA (IT) 1997-06-18 EP claimed
US-12623997-B2 Non-coordinating anion activators containing a cation with long chain alkoxy functionalization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-05-12 US disclosed
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-01-20 US disclosed
US-12503529-B2 Polymers of 4-substituted hexadiene and processes for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-12-23 US disclosed
US-12466902-B2 Non-coordinating anion type activators for use with polyolefin polymerization catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-11-11 US disclosed
EP-4051686-B1 NON-COORDINATING ANION ACTIVATORS CONTAINING A CATION WITH LONG CHAIN ALKOXY FUNCTIONALIZATION EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-10-01 EP disclosed
US-20030228976-A1 Catalyst system for the polymerization of olefins RESCONI LUIGI (IT) 2003-12-11 US disclosed
US-20020006863-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. 2002-01-17 US disclosed
EP-0669346-B1 Solid catalyst components for olefin polymerization and use thereof NIPPON OIL CO LTD (JP) 1998-06-03 EP disclosed
US-5604170-A EFFECTIVE CATALYST SUPPORT SATISFYING CERTAIN REQUISITES: PARTICLE DIAMETER, SPECIFIC SURFACE AREA, PORE VOLUME, SPECIFIC GRAVITY; SUBJECTED TO ULTRASONIC DISINTEGRATION NIPPON OIL COMPANY, LIMITED (JP) 1997-02-18 US disclosed
EP-0669346-A1 Solid catalyst components for olefin polymerization and use thereof NIPPON OIL CO. LTD. (JP) 1995-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes LEF1, TAF1, FLI1 HTR2A 3365/4885HTR6 4173/4885SIGMAR1 880/4885
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes AS3MT, AP1M1, AP3M1 HTR2A 4311/4885HTR6 4581/4885SIGMAR1 2968/4885
US-12623997-B2 Non-coordinating anion activators containing a cation with long chain alkoxy functionalization HCN4, SLC9A1, HCN1 HTR2A 3306/4885HTR6 2611/4885SIGMAR1 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.