Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31515802 | 0.98 | HTR2A (0.41) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL550006 | 0.95 | HTR2A (0.40) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Fluoride Ion SCHEMBL1130988 | 0.95 | HTR2A (0.40) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Iodide SCHEMBL3385271 | 0.95 | HTR2A (0.40) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL29602380 | 0.95 | HTR2A (0.40) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| SCHEMBL7113536 | 0.89 | HTR2A (0.36) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| SCHEMBL29480029 | 0.86 | HTR2A (0.38) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| SCHEMBL9158981 | 0.86 | SIGMAR1 (0.35) | HTR2AHTR6CYP2D6KDM4ELMNA | |
| Bicarbonate SCHEMBL31537215 | 0.86 | HTR2A (0.34) | HTR2AHTR6CYP2D6KDM4EMEN1 | |
| SCHEMBL7937810 | 0.82 | HTR2A (0.36) | HTR2AHTR6CYP2D6KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709586-B2 | Olefin polymerization catalyst and olefin polymerization process using the same | DAELIM INDUSTRIAL CO., LTD. (KR) | 2010-05-04 | — | — | US | disclosed |
| US-20070142221-A1 | Olefin polymerization catalyst and olefin polymerization process using the same | DAELIM INDUSTRIAL CO., LTD. | 2007-06-21 | — | — | US | disclosed |