Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480029 | 0.85 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL7113536 | 0.85 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL31515802 | 0.84 | HTR2A (0.41) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Fluoride Ion SCHEMBL1130988 | 0.82 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL550006 | 0.82 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Iodide SCHEMBL3385271 | 0.82 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Bromide SCHEMBL3381114 | 0.82 | HTR2A (0.45) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL29602380 | 0.82 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL9158981 | 0.78 | SIGMAR1 (0.35) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL18663160 | 0.77 | RET (0.39) | HTR2AHTR6SIGMAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776908-B1 | Catalyst composition having improved comonomer reactivity | UNIVATION TECH LLC (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6028151-A | Catalyst composition having improved comonomer reactivity | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
| US-5756416-A | COORDINATION CATALYST FOR OLEFIN POLYMERIZATION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0776908-A1 | Catalyst composition having improved comonomer reactivity | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-06-04 | — | — | EP | disclosed |