SCHEMBL3381695

SCHEMBL3381695

O=C(N[C@H](c1ccccc1)c1ccccn1)[C@@H]1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGFR P43088 1/20 0.49
MMP9 P14780 5/20 0.41
MMP2 P08253 4/20 0.41
HSD11B1 P28845 2/20 0.41
DRD2 P14416 3/20 0.40
MMP3 P08254 4/20 0.38
MMP8 P22894 4/20 0.38
MMP1 P03956 3/20 0.38
MMP12 P39900 2/20 0.38
MMP14 P50281 2/20 0.38
S1PR2 O95136 1/20 0.38
S1PR4 O95977 1/20 0.38
S1PR3 Q99500 1/20 0.38
ALDH1A1 P00352 1/20 0.38
ADAM17 P78536 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3381510 1.00 PTGFR (0.49) PTGFRMMP9MMP2HSD11B1DRD2
SCHEMBL3382814 1.00 PTGFR (0.49) PTGFRMMP9MMP2HSD11B1DRD2
SCHEMBL3385903 1.00 PTGFR (0.49) PTGFRMMP9MMP2HSD11B1DRD2
SCHEMBL29873273 1.00 PTGFR (0.49) PTGFRMMP9MMP2HSD11B1DRD2
SCHEMBL3380122 1.00 PTGFR (0.49) PTGFRMMP9MMP2HSD11B1DRD2
SCHEMBL3383880 0.93 PTGFR (0.42) PTGFRHSD11B1DRD2S1PR2S1PR4
SCHEMBL3383876 0.93 PTGFR (0.42) PTGFRHSD11B1DRD2S1PR2S1PR4
SCHEMBL3386587 0.92 KMT2A (0.43) PTGFRMMP2HSD11B1DRD2MMP3
SCHEMBL3386588 0.92 KMT2A (0.43) PTGFRMMP2HSD11B1DRD2MMP3
SCHEMBL3385850 0.91 PTGFR (0.46) PTGFRHSD11B1DRD2S1PR2S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608405-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL Veradermics, Incorporated (US) 2025-09-03 EP claimed
WO-2024091572-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2024-05-02 WO claimed
EP-1487442-B1 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR MERCK SERONO SA (CH) 2010-12-01 EP claimed
US-20050215605-A1 Thiazolidine carboxamide derivatives as modulators of the prostaglandin f receptor MERCK SERONO SA (CH) 2005-09-29 US claimed
US-20260144791-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS, INCORPORATED (US) 2026-05-28 US disclosed
US-20260144790-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS, INCORPORATED (US) 2026-05-28 US disclosed
US-20260130913-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2026-05-14 US disclosed
US-20260130912-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2026-05-14 US disclosed
US-20260130911-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2026-05-14 US disclosed
US-20260130916-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2026-05-14 US disclosed
US-20260130909-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2026-05-14 US disclosed
US-20260130914-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL VERADERMICS INCORPORATED (US) 2026-05-14 US disclosed
EP-1487442-B1 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR MERCK SERONO SA (CH) 2010-12-01 EP disclosed
US-20090215749-A9 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR LABORATOIRES SERONO S.A. (CH) 2009-08-27 US disclosed
US-20090215749-A9 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR LABORATOIRES SERONO S.A. (CH) 2009-08-27 US disclosed
US-20090215749-A9 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR LABORATOIRES SERONO S.A. (CH) 2009-08-27 US disclosed
US-20080255094-A1 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR LABORATOIRES SERONO S.A. (CH) 2008-10-16 US disclosed
US-20080255094-A1 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR LABORATOIRES SERONO S.A. (CH) 2008-10-16 US disclosed
US-20080255094-A1 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR LABORATOIRES SERONO S.A. (CH) 2008-10-16 US disclosed
US-20050215605-A1 Thiazolidine carboxamide derivatives as modulators of the prostaglandin f receptor MERCK SERONO SA (CH) 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144791-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL KIT, MC1R, MITF PTGFR 1068/4885MMP9 173/4885MMP2 963/4885
US-20260130909-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL MC1R, MC5R, SLC6A12 PTGFR 1571/4885MMP9 247/4885MMP2 801/4885
US-20260130914-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL MC1R, SLC8B1, SLC6A12 PTGFR 1144/4885MMP9 270/4885MMP2 941/4885
US-20260130911-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL MC1R, SLC6A12, SLC8B1 PTGFR 1748/4885MMP9 273/4885MMP2 771/4885
US-20260144790-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL SLC6A12, SLC8B1, MC1R PTGFR 1493/4885MMP9 634/4885MMP2 1436/4885
US-20260130916-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL KIT, MC1R, MITF PTGFR 1064/4885MMP9 192/4885MMP2 821/4885
US-20260130912-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL MC1R, SLC8B1, SLC6A12 PTGFR 1952/4885MMP9 194/4885MMP2 692/4885
US-20260130913-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL SLC8B1, MC1R, MC5R PTGFR 1260/4885MMP9 395/4885MMP2 1024/4885
US-20090215749-A9 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR PTGER4, PTGER2, PTGER1 PTGFR 9/4885MMP9 4351/4885MMP2 2710/4885
US-20080255094-A1 THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR PTGER4, PTGER2, PTGER1 PTGFR 9/4885MMP9 4351/4885MMP2 2710/4885
US-20050215605-A1 Thiazolidine carboxamide derivatives as modulators of the prostaglandin f receptor TBXA2R, CNR2, PTGDR PTGFR 16/4885MMP9 4645/4885MMP2 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.