Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384642 | 0.92 | MTNR1A (0.64) | MEN1KMT2AMTNR1AMTNR1BTRPV1 | |
| SCHEMBL3382278 | 0.88 | MEN1 (0.54) | MEN1KMT2AMTNR1AMTNR1BTRPV1 | |
| SCHEMBL3382094 | 0.88 | MTNR1A (0.72) | MEN1KMT2AMTNR1AMTNR1BPOLB | |
| SCHEMBL3382808 | 0.87 | MEN1 (0.61) | MEN1KMT2AMTNR1AMTNR1BTRPV1 | |
| SCHEMBL3385338 | 0.85 | MEN1 (0.61) | MEN1KMT2AMTNR1AMTNR1BTRPV1 | |
| SCHEMBL3262795 | 0.82 | MEN1 (0.54) | MEN1KMT2AMTNR1AMTNR1BTRPV1 | |
| SCHEMBL3227065 | 0.82 | MTNR1A (0.77) | MEN1KMT2AMTNR1AMTNR1BPOLB | |
| SCHEMBL3261766 | 0.82 | MEN1 (0.53) | MEN1KMT2AMTNR1AMTNR1BTRPV1 | |
| SCHEMBL3382527 | 0.81 | MEN1 (0.52) | MEN1KMT2AMTNR1AMTNR1BTRPV1 | |
| SCHEMBL3382755 | 0.81 | POLB (0.53) | MEN1KMT2AMTNR1AMTNR1BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |