SCHEMBL338291

SCHEMBL338291

CCCCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCCCC)(C(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.48
GPR84 Q9NQS5 7/20 0.48
PPARG P37231 7/20 0.48
PPARD Q03181 7/20 0.48
PPARA Q07869 7/20 0.48
HDAC11 Q96DB2 5/20 0.48
TSHR P16473 4/20 0.48
PTPN1 P18031 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48
ALOX15 P16050 1/20 0.48
PDE4A P27815 1/20 0.48
KMT2A Q03164 1/20 0.48
PDE3A Q14432 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3213688 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL5279943 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL5860239 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL11071652 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL2231045 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL5859421 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL344074 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL9953987 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL21269866 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL337636 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220265857-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2022-08-25 US disclosed
EP-3386484-B1 COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2022-03-30 EP disclosed
US-11285222-B2 Compositions and methods for delivery of agents MODERNATX, INC. (US) 2022-03-29 US disclosed
US-20200206362-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS Moderna TX, Inc. (US) 2020-07-02 US disclosed
US-20200206362-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS Moderna TX, Inc. (US) 2020-07-02 US disclosed
US-10556018-B2 Compositions and methods for delivery of agents ARES CAPITAL CORPORATION, AS AGENT 2020-02-11 US disclosed
US-10556018-B2 Compositions and methods for delivery of agents ARES CAPITAL CORPORATION, AS AGENT 2020-02-11 US disclosed
US-20190117798-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2019-04-25 US disclosed
US-20190117798-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2019-04-25 US disclosed
US-10207010-B2 Compositions and methods for delivery of agents MODERNATX, INC. (US) 2019-02-19 US disclosed
US-5521138-A COLOR DEVELOPMENT AND CRYSTALLIZATION RICOH COMPANY, LTD. (JP) 1996-05-28 US disclosed
US-5517228-A Apparatus for displaying a recording medium sheet and printing an image thereon RICOH CO., LTD. (JP) 1996-05-14 US disclosed
US-5432534-A Reversible thermosensitive coloring composition, recording medium, recording method, and image display apparatus using the recording medium RICOH COMPANY, LTD. (JP) 1995-07-11 US disclosed
US-5395433-A Containing electron donor coloring and electron acceptor compounds which react to induce color formation; printers for computers, facsimile apparatus RICOH COMPANY, LTD. (JP) 1995-03-07 US disclosed
US-5379058-A Recording apparatus using a thermosensitive recording medium RICOH COMPANY, LTD. (JP) 1995-01-03 US disclosed
US-5296439-A Support with reversible thermosensitive coloring recording layer containing electron donor coloring compound, electron acceptor which reacts to induce color formation RICOH COMPANY, LTD. (JP) 1994-03-22 US disclosed
EP-0576015-A1 Method of reversible recording Ricoh Company, Ltd (JP) 1993-12-29 EP disclosed
EP-0492628-A1 Reversible thermosensitive coloring composition, recording medium, recording method and image display apparatus using the recording medium Ricoh Company, Ltd (JP) 1992-07-01 EP disclosed
US-4157916-A Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1979-06-12 US disclosed
US-3950382-A STABILIZERS FOR POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190117798-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 CES2 1430/4885GPR84 3726/4885PPARG 3597/4885
US-10556018-B2 Compositions and methods for delivery of agents HDLBP, APOB, TSG101 CES2 1430/4885GPR84 3726/4885PPARG 3597/4885
US-20200206362-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 CES2 1430/4885GPR84 3726/4885PPARG 3597/4885
US-10207010-B2 Compositions and methods for delivery of agents HDLBP, APOB, TSG101 CES2 1430/4885GPR84 3726/4885PPARG 3597/4885
US-11285222-B2 Compositions and methods for delivery of agents HDLBP, APOB, TSG101 CES2 1430/4885GPR84 3726/4885PPARG 3597/4885
US-20220265857-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 CES2 1430/4885GPR84 3726/4885PPARG 3597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.