Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384167 | 0.74 | — | — | |
| SCHEMBL1026227 | 0.72 | — | — | |
| SCHEMBL854693 | 0.69 | THRB (0.44) | THRBLMNA | |
| SCHEMBL377551 | 0.68 | — | — | |
| SCHEMBL2332578 | 0.67 | THRB (0.42) | THRBLMNA | |
| SCHEMBL277640 | 0.67 | THRB (0.42) | THRBLMNA | |
| SCHEMBL10953174 | 0.67 | — | — | |
| SCHEMBL10427959 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL9677065 | 0.66 | — | — | |
| SCHEMBL3629399 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791851-B1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | ASTRAZENECA AB (SE) | 2010-12-01 | — | — | EP | disclosed |
| US-20080319231-A1 | Process for the Preparation of Alkyl Phosphinates | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| EP-1791851-A1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | AstraZeneca AB (SE) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006031180-A1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | ASTRAZENECA AB (SE) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319231-A1 | Process for the Preparation of Alkyl Phosphinates | PPIP5K2, AGPS, PHPT1 | THRB 3156/4885LMNA 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.