SCHEMBL277640

SCHEMBL277640

CCOCC(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
LMNA P02545 1/20 0.40
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL854693 0.90 THRB (0.44) THRBLMNA
SCHEMBL23581082 0.88 THRB (0.38) THRBLMNA
SCHEMBL14633846 0.87 THRB (0.33) THRBLMNA
SCHEMBL3985906 0.86 THRB (0.36) THRBLMNA
Acetic Acid SCHEMBL10508445 0.85 ALDH1A1 (0.37) THRBLMNAALDH1A1
SCHEMBL11760550 0.85 THRB (0.40) THRBLMNA
SCHEMBL1609095 0.84 THRB (0.35) THRBLMNA
SCHEMBL3312885 0.83 THRB (0.31) THRB
SCHEMBL28131148 0.83 TSHR (0.33) THRB
SCHEMBL9363446 0.83 ALDH1A1 (0.48) THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119114033-A Low-protein-adsorptivity blood perfusion adsorbent, preparation method thereof and blood perfusion device 泉州师范学院 2024-12-13 CN claimed
EP-1670836-A1 CATALYST SYSTEM FOR PRODUCING DIENE AND VINYL AROMATIC HOMOPOLYMERS AND COPOLYMERS BY ANIONIC POLYMERISATION Hellermann, Walter (DE) 2006-06-21 EP claimed
WO-2005035599-A1 CATALYST SYSTEM FOR PRODUCING DIENE AND VINYL AROMATIC HOMOPOLYMERS AND COPOLYMERS BY ANIONIC POLYMERISATION HELLERMANN WALTER (DE) 2005-04-21 WO claimed
EP-0917224-A1 Phosphonate additives for non-aqueous electrolyte in alkali metal electrochemical cells WILSON GREATBATCH LTD. (US) 1999-05-19 EP claimed
EP-4695246-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4582422-A1 METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Global Health Drug Discovery Institute (CN) 2025-07-09 EP disclosed
US-20250214997-A1 METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF GLOBAL HEALTH DRUG DISCOVERY INSTITUTE (CN) 2025-07-03 US disclosed
CN-119192666-A Cross-linked zwitterionic modified adsorbent, ultrahigh cross-linked zwitterionic modified adsorbent, preparation method of cross-linked zwitterionic modified adsorbent and blood perfusion device 泉州师范学院 2024-12-27 CN disclosed
CN-119114033-A Low-protein-adsorptivity blood perfusion adsorbent, preparation method thereof and blood perfusion device 泉州师范学院 2024-12-13 CN disclosed
WO-2024213653-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed
WO-2024056099-A1 METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 北京华益健康药物研究中心 2024-03-21 WO disclosed
CN-117720533-A MetTL3 inhibitor compound and pharmaceutical composition and application thereof 北京华益健康药物研究中心 2024-03-19 CN disclosed
EP-0523803-A1 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents STERLING WINTHROP INC. (US) 1993-01-20 EP disclosed
US-5175177-A 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS STERLING DRUG INC. (US) 1992-12-29 US disclosed
US-5105022-A Reacting in the presence of an acidic zeolite and/or a phosphate of zirconium, iron or aluminum; high conversion and catalyst selectivity BASF AKTIENGESELLSCHAFT (DE) 1992-04-14 US disclosed
EP-0302486-B1 PROCESS FOR THE PRODUCTION OF 1,2-DIALKOXYETHENES BASF Aktiengesellschaft (DE) 1992-03-18 EP disclosed
EP-0302486-A1 Process for the production of 1,2-dialkoxyethenes BASF Aktiengesellschaft (DE) 1989-02-08 EP disclosed
EP-0245854-A1 Process for producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-11-19 EP disclosed
US-4199572-A DERIVATIVES OF SISOMICINS BAYER AKTIENGESELLSCHAFT (DE) 1980-04-22 US disclosed
US-3994878-A Syntheses of 24R,25- and 24S,25-dihydroxycholesterol and alkanoyl derivatives thereof HOFFMANN-LA ROCHE INC. (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214997-A1 METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF METTL3, METTL14, METTL16 THRB 820/4885LMNA 3022/4885ALDH1A1 893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.