Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196061 | 0.91 | KDR (0.46) | KDRFGFR3ALDH1A1FLT3 | |
| SCHEMBL3382431 | 0.89 | KDR (0.44) | KDRFGFR3FLT3PIK3CAMTOR | |
| SCHEMBL3385521 | 0.88 | ALDH1A1 (0.55) | KDRFGFR3ALDH1A1FLT3 | |
| SCHEMBL3384812 | 0.83 | KDR (0.45) | KDRFGFR3FLT3PIK3CAMTOR | |
| SCHEMBL3383013 | 0.82 | RET (0.48) | KDRFGFR3FLT3PIK3CAMTOR | |
| SCHEMBL3384408 | 0.81 | KDR (0.50) | KDRFGFR3FLT3 | |
| SCHEMBL3385504 | 0.81 | RAF1 (0.56) | KDRFGFR3FLT3RAB9AMAPT | |
| SCHEMBL3381798 | 0.80 | KDR (0.48) | KDRFGFR3ALDH1A1 | |
| SCHEMBL3380938 | 0.79 | KDR (0.46) | KDRFGFR3FLT3 | |
| SCHEMBL3384061 | 0.79 | KDR (0.56) | KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |