Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 6/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.45 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11691929 | 0.84 | AKR1B1 (0.53) | AKR1B1TDP1CXCL8PTGS2AKR1B10 | |
| SCHEMBL2554055 | 0.82 | AKR1B1 (0.55) | AKR1B1TDP1CXCL8PTGS2BCAT2 | |
| SCHEMBL18301679 | 0.82 | AKR1B1 (0.55) | AKR1B1TDP1CXCL8PTGS2AKR1B10 | |
| SCHEMBL29718755 | 0.82 | AKR1B1 (0.55) | AKR1B1TDP1CXCL8PTGS2AKR1B10 | |
| SCHEMBL8573806 | 0.80 | AKR1B1 (0.64) | AKR1B1TDP1CXCL8PTGS2AKR1B10 | |
| Hydrochloric Acid SCHEMBL10582878 | 0.80 | AKR1B1 (0.53) | AKR1B1TDP1CXCL8PTGS2BCAT2 | |
| SCHEMBL29410826 | 0.79 | AKR1B1 (0.76) | AKR1B1TDP1CXCL8PTGS2AKR1B10 | |
| SCHEMBL30359 | 0.79 | AKR1B1 (0.76) | AKR1B1TDP1CXCL8PTGS2AKR1B10 | |
| SCHEMBL2004084 | 0.79 | AKR1B1 (0.52) | AKR1B1TDP1CXCL8PTGS2AKR1B10 | |
| SCHEMBL11669660 | 0.79 | AKR1B1 (0.52) | AKR1B1TDP1CXCL8PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1072580-B1 | PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID | IHARA CHEMICAL IND CO (JP) | 2010-12-01 | — | — | EP | disclosed |
| US-7491834-B2 | Chemical process | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20060163159-A1 | Chemical process | SYNGENTA CROP PROTECTION, INC. | 2006-07-27 | — | — | US | disclosed |
| EP-1506184-A2 | PROCESS FOR THE PREPARATION OF 3-ISOCHROMANONE | Syngenta Limited (GB) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003095442-A2 | PROCESS FOR THE PREPARATION OF 3-ISOCHROMANONE | SYNGENTA LIMITED (GB) | 2003-11-20 | — | — | WO | disclosed |
| US-6414186-B1 | REACTING METHYLPHENYLACETIC ACID WITH CHLORINE GAS, IN INERT SOLVENT, UNDER IRRADIATION WITH LIGHT OR IN PRESENCE OF RADICAL INITIATOR | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1072580-A1 | PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID | Ihara Nikkei Chemical Industry Co., Ltd. (JP) | 2001-01-31 | — | — | EP | disclosed |
| US-5112928-A | Coordination catalysts containing aluminum, vanadium and transition metal compounds | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060163159-A1 | Chemical process | HAO2, OGDH, TST | AKR1B1 2477/4885TDP1 4044/4885CXCL8 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.