SCHEMBL864384

SCHEMBL864384

OCCCCC(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
LMNA P02545 2/20 0.30
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TSHR P16473 1/20 0.30
CYP4F2 P78329 2/20 0.30
CYP4A11 Q02928 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2637189 0.97 LMNA (0.35) SMN1; SMN2CA1CA2LMNAALDH1A1
SCHEMBL8671685 0.97 LMNA (0.35) SMN1; SMN2CA1CA2LMNAALDH1A1
SCHEMBL6849263 0.97 LMNA (0.35) SMN1; SMN2CA1CA2LMNAALDH1A1
SCHEMBL879892 0.97 LMNA (0.35) SMN1; SMN2CA1CA2LMNAALDH1A1
SCHEMBL6852245 0.97 LMNA (0.35) SMN1; SMN2CA1CA2LMNAALDH1A1
SCHEMBL338407 0.97 SMN1; SMN2 (0.33) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL2780201 0.88
SCHEMBL2245008 0.84 GAA (0.39) MEN1KMT2ATSHRCYP4F2CYP4A11
SCHEMBL6650821 0.84
SCHEMBL2096698 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111792985-A Fluorine-containing heat transfer fluid and preparation method and application thereof 北京宇极科技发展有限公司 2020-10-20 CN claimed
US-20260001838-A1 NANOMATERIALS GUIDE THERAPEUTICS LLC (US) 2026-01-01 US disclosed
US-12435035-B2 Nanomaterials GUIDE THERAPEUTICS, LLC (US) 2025-10-07 US disclosed
CN-119684140-A Nanomaterial for the preparation of a nanoparticle 盖德治疗有限责任公司 2025-03-25 CN disclosed
CN-115175894-B Nanomaterial for the preparation of a nanoparticle 盖德治疗有限责任公司 2024-09-06 CN disclosed
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS BEAM THERAPEUTICS INC. 2023-10-19 US disclosed
CN-116887841-A Nanomaterials comprising ester-linked acetals 比姆医疗股份有限公司 2023-10-13 CN disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
EP-4103542-A1 NANOMATERIALS Guide Therapeutics, LLC (US) 2022-12-21 EP disclosed
CN-114874106-A Amino lipid and preparation method and application thereof 中山大学附属第七医院(深圳) 2022-08-09 CN disclosed
US-20070142443-A1 Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-21 US disclosed
US-20070073065-A1 Substituted optically active disphosphine compound TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-03-29 US disclosed
EP-1685092-A2 ASYMMETRIC REDUCTIVE AMINATION OF KETO ACID DERIVATIVES FOR PRODUCING AMINO ACID DERIVATIVES Takasago International Corporation (JP) 2006-08-02 EP disclosed
US-20060122418-A1 Method for producing an optically active beta-amino acid MATSUMURA KAZUHIKO 2006-06-08 US disclosed
US-7015348-B2 Method for producing an optically active β-amino acid TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-03-21 US disclosed
WO-2005028419-A2 ASYMMETRIC REDUCTIVE AMINATION OF KETO ACID DERIVATIVES FOR PRODUCING AMINO ACID DERIVATIVES TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-03-31 WO disclosed
US-20040023344-A1 Method for producing an optically activ beta-amino acid TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-02-05 US disclosed
EP-0225574-B1 NOVEL 1,4-DIHYDROPYRIDINES CONTAINING FLUORINE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS BAYER AG (DE) 1990-05-16 EP disclosed
US-4798840-A Coronary-active fluorine-containing 1,4-dihydropyridines BAYER AKTIENGESELLSCHAFT (DE) 1989-01-17 US disclosed
EP-0225574-A1 Novel 1,4-dihydropyridines containing fluorine, process for their preparation and their use as medicaments BAYER AG (DE) 1987-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001838-A1 NANOMATERIALS SLC10A1, NPC1L1, FABP1 SMN1; SMN2 1183/4885CA1 2972/4885CA2 2179/4885
US-20230331657-A1 NANOMATERIALS COMPRISING ESTER-LINKED ACETALS LIPA, SGMS1, SGMS2 SMN1; SMN2 575/4885CA1 788/4885CA2 4139/4885
US-20070142443-A1 Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives AADAT, BCAT2, BCAT1 SMN1; SMN2 4356/4885CA1 712/4885CA2 1358/4885
US-12435035-B2 Nanomaterials NPC1, NPC1L1, FABP1 SMN1; SMN2 1417/4885CA1 2550/4885CA2 2977/4885
US-20060122418-A1 Method for producing an optically active beta-amino acid AADAT, DAO, BCAT2 SMN1; SMN2 3286/4885CA1 1014/4885CA2 706/4885
US-20070073065-A1 Substituted optically active disphosphine compound DHPS, DOHH, DHODH SMN1; SMN2 4805/4885CA1 1750/4885CA2 690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.