Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849263 | 1.00 | LMNA (0.35) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL879892 | 1.00 | LMNA (0.35) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2637189 | 1.00 | LMNA (0.35) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL6852245 | 1.00 | LMNA (0.35) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL864384 | 0.97 | SMN1; SMN2 (0.32) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL338407 | 0.94 | SMN1; SMN2 (0.33) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2245008 | 0.87 | GAA (0.39) | MEN1KMT2ATSHRCYP4F2CYP4A11 | |
| SCHEMBL2780201 | 0.85 | — | — | |
| SCHEMBL10551402 | 0.84 | LMNA (0.32) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2095644 | 0.84 | LMNA (0.32) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672686-B1 | GANGLIOSIDE GM3 DERIVATIVE HAVING FLUORINATED CERAMIDE MOIETY | DAIKIN IND LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5583208-A | Ganglioside GM3 derivatives containing fluorine in ceramide portion | DAIKIN INDUSTRIES, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0672686-A1 | GANGLIOSIDE GM3 DERIVATIVE HAVING FLUORINATED CERAMIDE MOIETY | DAIKIN INDUSTRIES, LIMITED (JP) | 1995-09-20 | — | — | EP | disclosed |
| US-4876285-A | ANTHELMINTIC UTILITY | FMC CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |
| US-4318914-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4310545-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino) phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4305959-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4205085-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1980-05-27 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |