Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.59 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.54 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.54 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.48 |
| ▸ | MARK3 | P27448 | 2/20 | 0.48 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.48 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.46 |
| ▸ | ULK1 | O75385 | 2/20 | 0.45 |
| ▸ | ULK2 | Q8IYT8 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386206 | 0.95 | NTRK1 (0.54) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3388970 | 0.95 | NTRK1 (0.54) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3384238 | 0.91 | NTRK1 (0.59) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3385940 | 0.90 | MAP3K7 (0.65) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3387435 | 0.90 | TBK1 (0.59) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3384805 | 0.88 | MAP3K7 (0.56) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3388281 | 0.88 | MAP3K7 (0.56) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3388211 | 0.88 | ULK1 (0.49) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3388979 | 0.86 | NTRK1 (0.54) | NTRK1MAP3K7IRAK4TBK1MARK3 | |
| SCHEMBL3386219 | 0.86 | NTRK1 (0.54) | NTRK1MAP3K7IRAK4TBK1MARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056524-A1 | Compound | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056524-A1 | Compound | NR3C2, NR3C1, NR2E3 | NTRK1 70/4885MAP3K7 310/4885IRAK4 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.