Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124038 | 0.82 | AKR1C3 (0.51) | ALDH1A1LMNAAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL125385 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNARAB9ASMN1; SMN2HPGD | |
| SCHEMBL3384699 | 0.73 | KAT2B (0.56) | ALDH1A1LMNAAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL3322365 | 0.73 | MAPT (0.56) | ALDH1A1LMNAAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL9742270 | 0.72 | MAPT (0.56) | ALDH1A1LMNAAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL2323586 | 0.71 | AKR1C3 (0.69) | ALDH1A1LMNAAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL24455476 | 0.68 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2HPGDKAT2B | |
| SCHEMBL21315653 | 0.67 | SMN1; SMN2 (0.51) | ALDH1A1LMNAAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL29961863 | 0.67 | SMN1; SMN2 (0.51) | ALDH1A1LMNAAKR1C3AKR1C2AKR1B10 | |
| SCHEMBL11049649 | 0.67 | MAPT (0.59) | ALDH1A1LMNAAKR1C3AKR1C2AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205680-A2 | DICHROMOPHORE CARBONYL OR HETEROCYCLIC DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR DYEING KERATIN MATERIALS USING THIS DYE | L'Oreal (FR) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009040355-A2 | DICHROMOPHORE CARBONYL OR HETEROCYCLIC DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR DYEING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-04-02 | — | — | WO | disclosed |