Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DDX3X | O00571 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24455476 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRKAT2BHPGD | |
| SCHEMBL18037665 | 0.84 | GPR35 (0.50) | ALDH1A1TDP1TSHRKAT2BPOLB | |
| SCHEMBL27940262 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRKAT2BHPGD | |
| SCHEMBL3384697 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRKAT2BHPGDKMT2A | |
| SCHEMBL19899520 | 0.78 | ALDH1A1 (0.67) | ALDH1A1TDP1TSHRKAT2BHPGD | |
| SCHEMBL16831668 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRKAT2BHPGD | |
| SCHEMBL2045312 | 0.77 | HCAR3 (0.38) | ALDH1A1TDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL16831666 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRKAT2BHPGD | |
| SCHEMBL28204059 | 0.76 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRKAT2BHPGD | |
| SCHEMBL11620684 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRKAT2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158942-A2 | Direct hair dye composition comprising insoluble oxygenated compounds and processes | L'Oreal (FR) | 2010-03-03 | — | — | EP | claimed |
| US-7651534-B2 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL SA (FR) | 2010-01-26 | — | — | US | claimed |
| EP-1757326-B1 | Direct dying composition comprising insoluble oxygenated compounds and processes | OREAL (FR) | 2009-01-07 | — | — | EP | claimed |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| CN-119403534-A | Method for treating keratin fibres comprising a pretreatment or post-treatment step | 莱雅公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-119403533-A | Method for treating keratin fibres using a carnitine salt or a carnitine derivative | 莱雅公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118043027-A | Process for dyeing and/or lightening keratin fibres | 莱雅公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-4362892-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKYL (POLY)GLYCOSIDE, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AND AT LEAST ONE ALKALINE AGENT | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362896-A1 | COMPOSITION COMPRISING N,N-DICARBOXYMETHYLGLUTAMIC ACID, 1,3-PROPANEDIOL, AT LEAST ONE NONIONIC SURFACTANT, AT LEAST ONE ALKALINE AGENT AND/OR AT LEAST ONE DYE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-4362906-A1 | COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| CN-117479916-A | Composition comprising at least one alkyl (poly) glycoside, at least one fatty alcohol, at least one fatty acid and at least one alkaline agent | 欧莱雅 | 2024-01-30 | — | — | CN | disclosed |
| EP-1380820-A1 | Procedure of determining the composition of a dyeing product | L'OREAL S.A. (FR) | 2004-01-14 | — | — | EP | disclosed |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-07-31 | — | — | US | disclosed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| EP-1312344-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1312343-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL S.A. (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | KRT18, TUBB3, TUBB1 | ALDH1A1 2065/4885TDP1 3973/4885TSHR 4818/4885 |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | KRT18, DSG1, PLOD2 | ALDH1A1 188/4885TDP1 1969/4885TSHR 4670/4885 |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | KRT18, TUBB8, TUBA8 | ALDH1A1 1914/4885TDP1 4255/4885TSHR 4575/4885 |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | KRT18, TUBB3, TUBA3E | ALDH1A1 1615/4885TDP1 2678/4885TSHR 4749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.